Page 41 - Fpgee Question And Answer 2024 Edition

www.pharmacyexam.com Krisman

NTM Disorder tissues to a pharmacologically active free thiol
metabolite. This thiol metabolite is responsible for
Serotonin Deficiency MDD, OCD, PD, SAD, the reduction of the toxic effect of Cisplatin.
BN, PTSD, PMDD
961. (b) Clotrimazole (Mycelex) Troches are
Dopamine Deficiency Parkinsonism indicated for the treatment of oral candidiasis.
Each troche contains 10 mg of Clotrimazole. The
Dopamine Excess Schizophrenia recommended dose is one troche five times a day
for 14 consecutive days.
Acetylcholine Deficiency Myasthenia Gravis
962. (b) Fentanyl (Actiq) is an oral transmucosal
Histamine Excess Ulcer and allergic form of Fentanyl. It is Schedule II controlled drug. It
reactions is designed to dissolve slowly in the mouth in a
manner to facilitate transmucosal absorption. It is
Epinephrine Excess Cancer of Adrenal indicated for the management of breakthrough
Medulla cancer pain. It is available in six strengths equivalent
to 200, 400, 600, 800, 1200 and 1600 mcg of
Epinephrine Deficiency Depression Fentanyl base.

MDD: Major Depressive Disorder 963.(b) Candesartan (Atacand) is Angiotensin II
OCD: Obsessive-Compulsive Disorder receptor antagonist. It is indicated for the
PD: Panic Disorder treatment of hypertension. The normal therapeutic
SAD: Social Anxiety Disorder recommended dose of the drug is 16 mg once day.
BN: Bulimia Nervosa It is available in 4mg, 8mg, 16mg and 32mg of
PTSD: Posttraumatic Stress Disorder strengths.
PMDD: Premenstrual Dysphoric Disorder (PMDD)
964. (a) Renal impairment is the major toxicity of
957. (c) Brinzolamide (Azopt) is indicated for the Foscarnet (Foscavir). Frequent monitoring of
treatment of glaucoma and elevated intraocular creatinine clearance is required. Hydration may
pressure of the eyes. It is a carbonic anhydrase reduce the risk of nephrotoxicity. It is
inhibitor. It inhibits the carbonic anhydrase in the recommended that 750-1000 mL of normal saline or
ciliary processes of the eye and thus decreasing 5% dextrose solution should be given prior to the
aqueous humor production and reducing first infusion of Foscarnet to establish diuresis. With
intraocular pressure. The recommended dose is 1 subsequent infusions, 750-1000 mL of hydration
drop in affected eye(s) t.i.d. fluid should be given with 90-120 mg/kg of
Foscarnet, and 500 mL with 40-60 mg/kg of
958. (b) Tazarotene (Tazorac) topical cream and gel Foscarnet. Hydration fluid may need to be
are indicated for the treatment of psoriasis and decreased if clinically warranted.
acne.
After the first dose, the hydration fluid should be
959. (a) The principal adverse effect of Doxorubicin administered concurrently with each infusion of
is cardiac failure. The cumulative doses of more Foscarnet.
2
than 550 mg/mm induces cardiac toxicity.
It is indicated for the treatment of CMV retinitis and
960. (c) Amifostine (Ethyol) is indicated to reduce acyclovir-resistant mucocutaneous HSV infections in
the renal toxicity associated with repeated immunocompromised patients.
administration of Cisplatin. Amifostine is a prodrug
that is dephosphorylated by alkaline phosphate in

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