Page 45 - Fpgee Question And Answer 2024 Edition

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1001. (b) Poliomyelitis is an infectious virus disease Patients must be checked for normal renal function
caused by poliovirus. It affects the CNS. The virus is before initiating the therapy with Sotalol (Betapace
excreted in the feces of an infected person, and the AF).
disease is the most common where sanitation is
poor. Symptoms are normally reported 7 to 12 days 1008. (b) Sotalol is an antiarrhythmic agent. It is
after the infection. indicated for the maintenance of normal sinus
rhythm. It causes ventricular arrhythmia. To
1002. (d) Ketoacidosis is a life-threatening condition minimize the risk of arrhythmia, patients initiated
in which excessive ketones are present in tissues on Sotalol should be placed for a minimum of three
and body fluids. Nausea, vomiting, abdominal days under strict medical supervision. Betapace
tenderness, confusion, coma, extreme thirst, weight should not be substituted for Betapace AF because
loss, and acetone odor breath are common of significance difference between patient package
symptoms associated with Ketoacidosis. insert, dosing administration and safety
information.
1003. (c) K-PHOS tablets should be taken with a full
glass of water, with meals and at bed time. It 1009. (d) Estradiol (Climara) is indicated for the
increases urinary phosphate and pyrophosphate. It treatment of moderate to severe vasomotor
is used as a phosphorous supplement. symptoms associated with menopause. It should be
changed every week.
1004. (b) K-PHOS original contains potassium acid
phosphate as an active ingredient. It is classified as 1010. (b) Quinidine increases the serum
a urinary acidifier. It increases the bactericidal concentration of the following drugs:
activity of methenamine by enhancing its
conversion to formaldehyde in acidic urine. Warfarin Digoxin Haloperidol
Procainamide Nifedipine
1005. (d) Myocardial toxicity is the major side effect
associated with Daunorubicin and Doxorubicin. Quinidine has no clinically significant effects on the
Esmolol is a beta blocker. All these drugs must be pharmacokinetics of the following drugs:
used very carefully by patients suffering from CHF.
Diltiazem Mephyton Metoprolol
1006. (b) Glucagon is indicated for the treatment of Propafenone Propranolol Timolol
hypoglycemia associated with Insulin treated Tocainide
diabetic patients. It induces liver glycogen
breakdown, releasing glucose from the liver. Blood Its pharmacokinetics are also unaffected by
glucose concentration rises within 10 minutes of cigarette smoking.
injection and maximum concentrations are attained
within half an hour after injection. Hepatic sources 1011. (a,b and c) Interferon beta-1b (Betaseron),
of glycogen are necessary to produce an anti- Lioresal (Baclofen), Dantrolene (Dantrium) and
hypoglycemic effect. Interferon beta -1a (Avonex) are indicated for the
treatment of multiple sclerosis. Sparfloxacin
1007. (a) Sotalol (Betapace) is indicated for the (Zagam) is an antibacterial agent indicated for the
treatment of documented ventricular arrhythmia. It treatment of community acquired pneumonia.
is a beta blocker. It is mainly eliminated via the
kidneys through glomerular filtration and to a small 1012. (c) Permethrin is classified as a scabicidal
degree by tubular secretion. agent. It is indicated for the treatment of infestation
with Sarcoptes scabiei (scabies).
There is direct relationship between creatinine
clearance and elimination of Sotalol (Betapace).

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