Page 44 - Fpgee Question And Answer 2024 Edition

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986. (b) Patients on Nilutamide (Nilandron) therapy 993. (a) Severe fluid retention or edema is reported
reported a delay in adaptation to the dark, ranging with Docetaxel (Taxotere). It should be carefully
from seconds to a few minutes, when passing from prescribed to patients suffering from CHF.
lighted areas to dark areas. Patients who experience
this effect should be cautioned about driving at 994. (c) Pentoxifylline (Trental) is indicated for the
night or through tunnels. This effect can be reduced treatment of peripheral vascular disease. It is
or alleviated by wearing tinted glasses. classified as a hemorheological agent, i.e. an agent
that affects the blood viscosity. The recommended
987. (b) Rifapentine (Priftin) inhibits DNA dose is 400 mg three times a day with meals.
dependent RNA polymerase enzymes. It is indicated
for the treatment of pulmonary tuberculosis. 995. (c) Desmopressin (Stimate) is indicated for the
treatment of Von Willebrand’s disease and
988. (b) Lepirudin (Refludan) is indicated for the Hemophilia A. It is a synthetic analog of the natural
treatment of Heparin-Induced Thrombocytopenia. pituitary hormone Vasopressin. It is available in
HIT is described as an allergy-like adverse reaction nasal spray form. The dose is administered by nasal
to heparin. The recommended bolus dose of drug is insufflation, one spray per nostril, to provide a total
0.4 mg/kg/body weight/hour slowly intravenously, dose of 300mcg.
followed by 0.15mg/kg/body weight/hour as a
continuous I.V. infusion. 996. (d) Pancrelipase microspheres should be
swallowed whole. Administration of capsules on
989. (c) Rifampin (Rifadin) causes a reddish empty stomachs with applesauce (acidic food) or
discoloration of the urine, sweat, sputum and tears. chewing them may destroy their enteric coating and
It is indicated for the treatment of tuberculosis. inactivated them with gastric acid. If a capsule’s
content is mixed with applesauce or any other
990. (a) Rifampin/Isoniazid (Rifamate) therapy acidic food, it should be swallowed immediately.
should be closely monitored by regularly checking
the serum transaminase level. Isoniazid therapy is 997. (b) Ursodiol (Urso) is a naturally occurring bile
associated with severe and fatal hepatitis. Rifater acid found in humans. It is indicated for the
contains Rifampin, Isoniazid and Pyrazinamide. treatment of biliary cirrhosis. It is also known as
Ursodeoxycholic acid. The recommended dosage is
991. (a) Quinupristin/dalfopristin (Synercid) is 13-15mg/kg/day administered in four divided doses
specifically indicated for the treatment of with food.
Vancomycin Resistant Enterococcus Faecium. The
recommended dose of drug is 7.5 mg/kg every 8 998. (a) Bumetanide (Bumex) is classified as a loop
hours. Inflammation, pain, edema, diuretic. It is indicated for the treatment of edema
pseudomembranous colitis, vasodilation and associated with CHF, nephrotic syndrome and
pancreatitis are reported side effects of the drug. hepatic cirrhosis. Hypokalemia and electrolyte loss
The recommended dose is 7.5 mg/kg every eight are major side effects of the drug. The
hours. recommended dose is 0.5 to 2 mg per day.

992. (d) Docetaxel (Taxotere) therapy should be 999. (c) Ototoxicity, cumulative renal toxicity,
closely monitored for abnormal liver function and myelosuppression, nausea and vomiting are
neutropenia. Therapy should only be initiated if reported side effects of Cisplatin.
bilirubin, SGOT/SGPT levels and neutropenia counts
fall in the normal limit. It is indicated for the 1000. (c) Myocardial toxicity is the principal side
treatment of breast cancer and Non-small lung effect of Doxorubicin. It is dose related. It should be
cancer. carefully prescribed to patients suffering from CHF.

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