Page 36 - Fpgee Question And Answer 2024 Edition

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Sargramostim (Leukine) is a recombinant human with 6 to 8 ounces of plain water only, should be
granulocyte macrophage colony stimulating factor. administered for a period of 3 months. Beverages
It is mainly indicated for myeloid reconstitution other than plain water (including mineral water),
after autologous bone marrow transplantation. food, and some medications are likely to reduce the
absorption of Tiludronate (Skelid).
Pegfilgrastim (Neulasta) is a covalent conjugate of
recombinant methionyl human G-CSF (Filgrastim) Patients should not lie down for at least 30 minutes
and monomethoxypolyethylene glycol. after taking the medication.

It is indicated to decrease the incidence of infection, It should not be taken within 2 hours of food.
as manifested by febrile neutropenia, in patients Calcium or mineral supplements should be taken at
with non-myeloid malignancies receiving least 2 hours before or two hours after Tiludronate
myelosuppressive anti-cancer drugs associated with (Skelid). Aluminum- or magnesium-containing
a clinically significant incidence of febrile antacids, if needed, should be taken at least two
neutropenia. It is also indicated to increase survival hours after taking Tiludronate (Skelid).
in patients acutely exposed to myelosuppressive
doses of radiation. Tiludronate (Skelid) should not be taken within 2
hours of indomethacin.
Tbo-Filgrastim (Granix) is indicated to reduce the
duration of severe neutropenia in patients with Each tablet for an oral administration contains 240
non-myeloid malignancies receiving mg of Tiludronate sodium which is the molar
myelosuppressive anti-cancer drugs associated with equivalent of 200 mg tiludronic acid. It is available
a clinically significant incidence of febrile in once daily dosing. It cannot be given to patients
neutropenia. suffering from renal function impairment.

Darbepoetin alfa (Aranesp) is indicated for the 918. (d) During acute attacks of asthma, Total Lung
treatment of anemia due to chronic kidney disease Capacity (TLC), lung's Functional Residual Volume
(CKD), including patients on dialysis and patients (FRV), Residual Volume (RV) and WBC counts are
not on dialysis. elevated and Forced Expiratory Volume (FEV) is
generally reduced. These all are important terms to
It is also indicated for the treatment of anemia in identify the extent of airway obstruction during
patients with non-myeloid malignancies where acute attacks of asthma.
anemia is due to the effect of concomitant
myelosuppressive chemotherapy, and upon 919. (b) Since the child has suffered from nausea
initiation, there is a minimum of two additional and vomiting for the past few days, it is advisable to
months of planned chemotherapy. admit him immediately to the hospital to prevent
further complications.
915. (d) All. The overdose symptoms of Codeine are
respiratory depression with Cheyne-Stokes 920. (d) PEFR is generally defined as Peak Expiratory
respiration, hypoxia, pinpoint pupil construction, Flow Rate. The patient should measure and record
pulmonary edema and circulatory collapse. PEFR twice daily for 2 weeks. The PEFR should be
measured immediately upon rising in the morning,
916. (b) Hemoglobin test usually measures 1 gram and then 10 to 12 hours after the first PEFR
of hemoglobin per deciliter volume of the blood. measurement. The “personal best” PEFR is
generally indicated by the highest PEFR found in the
917. (d) Tiludronate (Skelid) is indicated for the 2-week period.
treatment of Paget’s disease of bone. A single 400-
mg daily oral dose of Tiludronate (Skelid), taken

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