Page 40 - Fpgee Question And Answer 2024 Edition

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949.(a) Vancomycin (Vancocin) enema is generally Fenofibrate is a lipid regulating agent. It is indicated
indicated for the treatment of antibiotic induced P. for the treatment of hypercholesterolemia &
colitis caused by clostridium difficile. hypertriglyceridemia.

950. (b) The normal therapeutic serum Pancreatitis, cholelithiasis, nausea and vomiting,
concentration of potassium should be between 3.5 diarrhea, and renal toxicity are reported side effects
and 5 mEqs/L. of the drug. The recommended dose is 67 mg per
day with meal.
951.(d) Pentobarbital and Secobarbital are short-
acting barbiturates. Their onset of action is 10 to 15 954.(d) Aluminum and Magnesium containing
minutes, and their duration of action is about 3 to 4 antacids reduce the rate (Cmax) and extent of
hours. absorption (AUC) of Cefdinir (Omnicef) by 40%.

Long acting Onset of action Duration If antacids are required during Cefdinir (Omnicef)
therapy, they should be administered 2 hours
Phenobarbital 1 hour or longer 10 to 12 hrs before or after Cefdinir (Omnicef) therapy.

Intermediate Onset of action Duration Iron supplements reduce the extent of absorption
of the drug by 80%. The iron supplements should be
Amobarbital 3/4 to 1 hour 6 to 8 hrs taken 2 hours before or after Cefdinir (Omnicef)
Butabarbital therapy.

Short acting Onset of action Duration Probenecid inhibits the renal excretion of Cefdinir
(Omnicef). This increases the blood concentration
Pentobarbital 10 to 15 minutes 3 to 4 hrs and toxicity of the drug. Simultaneous
Secobarbital 10 to 15 minutes 3 to 4 hrs administration of these two drugs is strictly
prohibited.
952.(a) Ritonavir (Norvir) oral solution contains 49%
alcohol. It should be carefully prescribed with drugs 955.(b) Paricalcitol (Zemplar) is a synthetically
producing disulfiram-like reactions such as manufactured vitamin-D analog. It is indicated for
Metronidazole, Chlorpropamide, Cefoperazone, the prevention and treatment of secondary
Cefamandole, Cefotetan, and Disulfiram. hyperparathyroidism associated with chronic renal
failure. The recommended initial dose is 2.8 to 7
Ritonavir is classified as an antiviral drug. It is a mcg, administered as a bolus dose no more
protease inhibitor. It is indicated for the treatment frequently then every other day at any time during
of HIV infections. The recommended dose is 600 mg dialysis.
b.i.d.
956. (d) The transmitting substance, a chemical that
Nausea, vomiting, diarrhea, anorexia, flatulence, causes the impulses to transfer from one axon to
and asthenia are reported side effects of the drug. another is known as a neurotransmitter (NTM).
There are five principal neurotransmitters in the
953.(b) Warfarin (Coumadin) should be carefully brain. They account for various functions and the
prescribed with Fenofibrate (Tricor). The dosage of deficiency of particular neurotransmitters may
Warfarin (Coumadin) should be reduced to maintain cause specific disorders.
the desired prothrombin time/INR in order to
prevent bleeding complication.

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