Page 34 - Fpgee Question And Answer 2024 Edition

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edema associated with CHF, nephrotic syndrome 903. (a) Valproic acid generally increases the
and hepatic cirrhosis. The recommended dose is 40 concentration of GABA. It is an inhibitory
mg to 80 mg per day. Hypokalemia and electrolyte neurotransmitter; so by increasing the
loss are reported side effects of the drug. concentration of GABA antiepileptic action is
produced.
902.(c) Diflunisal (Dolobid) is a prodrug. A prodrug
is a medication or compound that, after It is available under Depakene brand name. It is
administration, is metabolized into a available in 125 mg, 250 mg and 500 mg of oral
pharmacologically active drug. Diflunisal is classified strengths.
as an NSAID. It may cause ulcers and G.I. bleeding. It
is indicated for the treatment of pain. The The major adverse effects reported with Valproic
recommended therapeutic dose is 500 mg to 1000 acid (Depakene) are hypoprothrombinemia and
mg per day in divided doses. hepatotoxicity. It is generally considered as a drug
of choice for the treatment of all kinds of epilepsies.

904. (d) Lorazepam (Ativan) injection reduces the
severity and duration of nausea and vomiting

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