Page 31 - Fpgee Question And Answer 2024 Edition

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876.(b) Diabetes is the leading cause of renal In combination with Olanzapine (Zyprexa), it is
failure in the world. Enalapril (Vasotec) or any other indicated for the treatment of:
ace inhibitor may reduce the risk of renal
insufficiency by 50% and end-point death 1. Acute treatment of depressive episodes
associated with diabetes. associated with Bipolar I Disorder.

877. (b) Theophylline sodium glycinate elixir 2. Treatment resistant depression (Major
(Synophylate) and Theophylline elixir (Elixophyllin) Depressive Disorder in patients, who do not
contain 10 to 40% alcohol and should be avoided respond to 2 separate trials of different
with Disulfiram (Antabuse) to prevent disulfiram- antidepressants of adequate dose and duration in
like reactions. the current episode).

878. (d) Amitriptyline (Elavil) is classified as a Fluoxetine (Prozac) monotherapy is not indicated
tricyclic antidepressant. It has the highest sedation for the treatment of depressive episodes associated
property among all the antidepressant agents and with Bipolar I Disorder or the treatment of
may be more preferable to use for the treatment of treatment resistant depression.
depression with anxiety disorder.
880. (a) Gold-compound (Auranofin), Methotrexate
The recommended dose is 75 mg to 150 mg at bed and Probenecid (Benemid) may increase the risk of
time. Anticholinergic side effects such as dryness of nephrotoxicity when used simultaneously with
mouth, constipation, blurred vision and urinary Ketorolac (Toradol). Concurrent use may not be
retention are reported with the drug. recommended.

879. (c) Fluoxetine (Prozac) is a potent and selective Concurrent use of Cefotetan (Cefotan) with
serotonin reuptake inhibitor. Each Pulvule® contains Ketorolac (Toradol) may aggravate the bleeding
Fluoxetine hydrochloride equivalent to 10mg, tendency of patients by inhibiting aggregation of
20mg, or 40mg of Fluoxetine. platelets. Concurrent use may require close
supervision.
Prozac Weekly™ capsules, a delayed-release
formulation, contain enteric-coated pellets of 881. (a) Carbamazepine (Tegretol) is indicated for
Fluoxetine hydrochloride equivalent to 90mg of the relief of pain due to trigeminal neuralgia and
Fluoxetine. glossopharyngeal neuralgia.

It is indicated for the treatment of: It is structurally related to Tricyclic Antidepressant
and should be carefully used in patients with TCA
1. Acute and maintenance treatment of Major allergy. It is also used for alcohol withdrawal
Depressive Disorder. treatment. It rapidly relieves anxiety and distress in
acute alcohol withdrawal treatment. It is also
2. Acute and maintenance treatment of obsessions indicated for the treatment of partial and grand mal
and compulsions in patients with Obsessive seizures.
Compulsive Disorder (OCD).
For the treatment of simple and grand mal seizures,
3. Acute and maintenance treatment of binge- Phenytoin (Dilantin), Phenobarbital and Mysoline
eating and vomiting behaviors in patients with (Primidone) are generally used. For the treatment
moderate to severe Bulimia Nervosa. of absence seizure, Ethosuximide (Zarontin),
Valproate sodium (Depakote) and Valproic acid
4. Acute treatment of Panic Disorder, with or (Depakene) are commonly used.
without agoraphobia.

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