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Ketoacidosis: 752.(b) Nitrostat IV > Nitrostat SL > Nitrolingual
Spray > Nitro Dur TDS
1. Presence of Acetone and glucose in urine
2. Loss of appetite, abdominal pain Below is the summary of various nitroglycerine
3. Acetone breath products and their onset of actions.
4. Rapid pulse
Dosage forms Onset of action (min)
748. (c) Amiloride (Midamor) is a potassium sparing
+
+
diuretic that acts by inhibiting the Na K ATP ase I.V. 1 to 2
activity. It is indicated for the treatment of edema Sublingual 1 to 3
associated with CHF, hepatic cirrhosis, and Translingual spray 2
nephrotic syndrome. Hyperkalemia, lethargy, Transmucosal tab 1 to 2
weakness, electrolyte loss and hypotension are Oral, sustain release 20 to 45
reported side effects of the drug. The Topical ointment 30 to 60
recommended dose is 5 to 10 mg per day. Transdermal 30 to 60
749. (c) Digoxin (Lanoxin) is classified as an
inotropic agent, an agent that increases the force of 753.(c) Dissolve one tablet under the tongue at the
contraction of the heart. It is indicated for the acute onset of an angina attack; repeat every 5
treatment of atrial flutter, atrial fibrillation, and minutes until complete relief is achieved. Do not
CHF. It should not be used for the treatment of exceed more than 3 tablets within 15-minute
ventricular fibrillation since it may induce interval.
automaticity to ventricles, which may worsen the
ventricular fibrillation. The recommended dose is 754.(c) I.V. administration of 1/6 molar sodium
0.125mg to 0.25mg per day. The therapeutic serum lactate solution causes a marked decrease in the
concentration of the drug shall be laid between 0.7 cardio toxic effects of Quinidine. Administration of
and 1.4 ng/ml. Diazepam or any other benzodiazepines is
contraindicated since profound CNS depression may
Anorexia, hypotension, edema, ventricular occur during Quinidine toxicities.
fibrillation and convulsion are reported side effects
of the drug. The drug should be carefully prescribed 755.(c) Ringing in the ear, headache, nausea,
with other agents that may induce hypokalemia. vertigo and vision disturbances are common side
effects reported with quinidine.
750. (b) Myxedema is a thyroid disorder that occurs
due to hyposecretion of the thyroid hormone. It 756.(a) Quinidine sulfate contains the highest
would normally reduce the rate of excretion of the amount of anhydrous quinidine alkaloids. Below is
Digoxin (Lanoxin) and may increase the serum the summary of various salts of quinidine and their
concentration and its toxicities in the blood. Digoxin alkaloid contents:
(Lanoxin) dose should be reduced and closely
monitored in such patients. Name %
751. (b) Amrinone has vasodilation as well as Quinidine sulfate 83%
positive inotropic (increase the strength of muscular Quinidine gluconate 62%
contraction) properties. It is usually known as an Quinidine polygalacturonate 60%
Inodilator (Inotropic + Dilation). It is indicated for Quinidine hydrochloride 0
the treatment of heart failure. The prolonged use of
Amrinone may cause severe thrombocytopenia.
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