Page 25 - Fpgee Question And Answer 2024 Edition

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pregnancy for the other contraceptives are listed
below, from low risk to high risk. Insulins Durations of
action (hours)
Oral contraceptives >IUD > Condoms > Diaphragm >
Vaginal sponges Extended Insulin Zn Suspension > 36 hours
(Ultralente)
741. (b) Betamethasone > Triamcinolone >
Hydrocortisone > Cortisone Protamine Zn Insulin Suspension 36 hours
(PZI)
Below is the list of various corticosteroids with their
half-lives. Insulin Zn Suspension (Lente) 24 Hours

Glucocorticoid Equivalent Half-life Isophane Insulin Suspension 24 Hours
Dose (mg) (hours) (NPH)

Short Acting Prompt Insulin Zn Suspension 12-16 hours
(Semilente)
Cortisone 25 8-12
Hydrocortisone 20 8-12 Insulin Regular 6 to 8 Hours

Intermediate Acting Insulin Lispro 2 to 3 Hours

Methylprednisolone 4 18-36
Prednisolone 5 18-36 745.(c) Insulin is secreted by the beta cells of the
Prednisone 5 18-36 pancreas. It is the principal hormone required for
Triamcinolone 4 18-36 glucose metabolism. Insulin preparations are
generally extracted from pork or beef. Human
Long Acting insulin is derived by a biosynthetic process from the
strains of E.coli. It is the least antigenic in nature
Betamethasone 0.6-0.75 36-54 compared to pork and beef insulins.
Dexamethasone 0.75 36-54
746.(d) “Insulin resistant” is defined as when the
patient needs more than 200 units of insulin per
742.(d) Fludrocortisone has the highest day.
mineralocorticoid property. It is indicated for the
treatment of primary and secondary adrenocortical 747.(d) All. Below is the summary of symptoms
insufficiency in Addison’s disease, and for the associated with each disease:
treatment of salt-losing adrenogenital syndrome.
Hypoglycemia:
743. (b) Aminoglutethimide is indicated for the
treatment of Cushing’s syndrome (excessive 1. Absence of glucose and ketone in urine
secretion of adrenocorticoids). It inhibits the 2. Hunger, numbness and tingling
enzymatic conversion of cholesterol to 3. Confusion, diplopia, convulsions
pregneninolone, and thus reduces the synthesis of 4. Tachycardia
glucocorticoids and mineralocorticoids. 5. Confusion

744. (b) Below is the summary of different insulins
and their durations of action.

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