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IgA: It is the major immunoglobulin secreted in immune cells called B-cells. Recognized as the
external body secretions such as saliva, tears and fastest growing human tumor, Burkitt lymphoma is
urine. It accounts for 10% of total immunoglobulins. associated with impaired immunity and is rapidly
fatal if left untreated.
IgE: This immunoglobulin plays an important
role in combating helminth and allergy reactions However, intensive chemotherapy can achieve long-
produced by drugs, pollens or foods. The level of term survival in more than half the people with
this immunoglobulin is found to be highly elevated Burkitt lymphoma.
in patients with allergy condition. Such as asthma
and hay fever. Burkitt lymphoma is named after British surgeon
Denis Burkitt, who first identified this unusual
IgD: It accounts for 1% of total disease in 1956 among children in Africa.
immunoglobulins. It serves as an antigen receptor
site in the early stages of immune response. In Africa, Burkitt lymphoma is common in young
children who also have malaria and Epstein-Barr,
386. (c) Burkitt lymphoma is a form of non- the virus that causes infectious mononucleosis.
Hodgkin's lymphoma in which cancer starts in
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