1.
(b)
Green plants, with the help of sunlight and
in the presence of enzymes, synthesize organic
compounds like starch from inorganic compounds
like CO2 and H2O. This is known as photosynthesis.
Chloroplast is the organelle to perform photosynthesis.
Plants that are devoid of chloroplast cannot
synthesize starch.
2.
(c)
Mitochondria is known as the "power house
of the cell". It is involved in the continuous
production of energy. It releases necessary
energy for different functions of the cell through
processes like respiration, electron transport
and oxidative phosphorylation.
3.
(a)
Each cell has two main components - Cytoplasm
and the nucleus. Usually there is a nucleus
in the cell. Organisms without any cytoplasmic
organizations and devoid of definite nuclear
material are grouped as Akaryota. (e.g. Virus)
Organisms having a primitive type of nucleus
in cell, are classified Prokaryota. (e.g. Bacteria
and Blue green algae.) Organisms having a cell
with a well developed nucleus are grouped as
Eukaryota. (e.g. Fungi-yeast, mushroom).
4.
(a)
Cell division is a very complex process. There
are two main types of cell division:
1.
Mitosis
2. Meiosis
1
Mitosis: In this type of cell division, chromosomes
are equally distributed in each daughter cell.
As a result, the number of chromosomes in the
daughter cells is the same as that in the mother
cell. It is also known as equational division.
(e.g. Somatic cells division)
2. Meiosis: In this type of cell division, chromosomes
are divided in half of the original mother cells,
therefore the daughter cells consist of half
the number of chromosomes that are in the mother
cell. (e.g. reproductive or sex cells division)
5.
(c)
Nitrogen fixing bacteria on root nodules of Leguminous
plants are known as Rhizobium. They fix the atmospheric
nitrogen and convert it into ammonia. The nitrogen
fixing bacteria are also known as nitrifying bacteria.
Azobacteria are present in the soil. They convert
atmospheric nitrogen into nitrates and nitrites.
In this way, they increase the fertility of the
soil. These ammonium nitrates and nitrites are
then absorbed by plants to obtain nitrogen.
6.
(b)
RNA consists of ribose pentose sugar. Unlike DNA,
it consists of only one polynucleotide chain.
It also contains two purine and pyrimidine bases.
Uracil (U) is the nitrogen base which is present
in RNA but absent in DNA. Thus RNA contains Adenine
(A) and Guanine (G) as purine bases, and Cytosine
(C) and Uracil (U) as pyrimidine bases.
7.
(c)
Glycogen is considered the principal storage form
of glucose and is found mainly in the liver and
muscle, with kidney and intestines adding minor
storage sites. Glycogen is formed by the liver
from glucose in the bloodstream and is stored
in the liver. Glycogen is also produced by and
stored in muscle cells; during short periods of
strenuous activity, energy is released in the
muscles by direct conversion of glycogen to lactic
acid. During normal activity, energy is released
by metabolic oxidation of glucose to lactic acid.
Glycogenesis (formation of glycogen from glucose)
and glycogenolysis (break down of glycogen into
glucose) are two principal mechanisms by which
blood glucose level has been maintained.
8.
(b)
Ligaments are strong flexible white fibrous bands.
They bind the articular surfaces of bones together.
They provide necessary freedom for the bones as
well as protect joints from external injury and
bones from dislocation. Tendons are white bands
which join muscles with bones while ligaments
hold bones together at joints and are inelastic.
9.
(c)
The primary type of lipids found in the cell
membrane are phospholipids, cholesterol and
glycolipids. Out of these, phospholipids play
an important role in controlling the movement
of substances into and out of the cell. In general,
lipid soluble substances are allowed to move
into the cell whereas water soluble molecules
are restricted or not allowed to pass through
the cell membrane.
10.
(a)
Bile (or gall) is a bitter, greenish-yellow
alkaline fluid secreted by the liver of most
vertebrates. It helps in the complete digestion
of fats by reducing surface tension. It also
activates the enzyme lipase. It serves as a
good solvent for fats and fat-splitting enzymes.
Bile also helps in absorption of carbohydrates,
fats, fat soluble vitamins and proteins.
11.
(c)
The region in space where an electron is likely
to be found is called an orbital. There are
different kinds of orbitals with different sizes
and shapes. The orbital at the lowest energy
level is defined as a 1s orbital. It is a sphere
with its center at the nucleus of the atom.
The next higher energy level is called a 2s
orbital. It is larger than a 1s orbital. Since
it has a higher energy level, it has lower stability
compared to a 1s orbital. This is because the
average distance between the nucleus and electrons
in a 2s orbital is greater than in a 1s orbital.
The next three orbitals are of equal energy,
known as 2p orbitals. They are dumbbell-shaped.
They are further differentiated by the names
2px, 2py, and 2pz, where the x, y, and z refer
to the corresponding axes.
12. (d) In the covalent
bond, two atoms are joined by sharing electrons.
Both nuclei are held by the same electron cloud.
However, in most cases the two nuclei do not
share the electrons equally. This happens when
one atom has more electron withdrawing power
than the other atom. At this time the electron
cloud is denser on one atom. This result in
one end of the bond being relatively negative
and the other end being relatively positive.
Such a bond is said to be a polar bond or to
possess polarity. The bond possesses polarity
when joins atoms have different tendency to
attract electrons. This property of the atom
is called electronegativity. Out of the given
choices, fluorine (F) possess the highest electronegativity.
F > O > Cl, N > Br > C, H
13. (c) The molecular
formula for methyl chloride is CH3Cl. The mass
of a chlorine atom in methyl chloride is 35.5
gm/mole. The molecular weight of methyl chloride
is 50.5 gm/mole (1C = 12, 3H = 3 and 1Cl = 35.5).
Therefore, the % mass of chlorine in methyl
chloride will be 35.5/50.5 = 70%
13. (c) The molecular formula for methyl chloride is CH3Cl. The mass of a chlorine atom in methyl chloride is 35.5 gm/mole. The molecular weight of methyl chloride is 50.5 gm/mole (1C = 12, 3H = 3 and 1Cl = 35.5). Therefore, the % mass of chlorine in methyl chloride will be 35.5/50.5 = 70%
14. (b) Isotopes
are defined as forms of the same chemical element
that differ only by the number of neutrons in
their nucleus. Most elements have more than
one naturally occurring isotope. The atomic
number "Z" is the same in such elements, however
their atomic mass "A" is different due to differ
numbers of neutrons in the nucleus of the atom.
15. (a) The alkali
metals, found in group 1 of the periodic table
(formerly known as group IA), are very reactive
metals that do not occur freely in nature. These
metals have only one electron in their outer
shell. Therefore, they are ready to lose that
one electron in ionic bonding with other elements.
As with all metals, the alkali metals are malleable,
ductile, and are good conductors of heat and
electricity. The alkali metals are softer than
most other metals. Cesium and francium are the
most reactive elements in this group. Alkali
metals can explode if they are exposed to water.
The Alkali Metals are: lithium (Li), Sodium
(Na), Potassium (K), Rubidium (Rb), Cesium (Cs),
Francium (Fr).
17. Home ovulation tests usually detect a preovulatory surge in which of the following in the urine?
a. Prolactin
b. Oestrogen
c. Oxytocin
d. Progesterone
e. Luteinizing hormone
Answer: (e). An ovulation home test is used by women to help determine the time in the menstrual cycle when getting pregnant is most likely. The test detects a rise in luteinizing hormone (LH) in the urine. A rise in this hormone signals the ovary to release the egg.
18. Which of the following information is TRUE ABOUT anaerobic respiration? (Select All that apply)
a. Waste products are carbon dioxide and water.
b. It may produce between 36 and 38 ATP molecules.
c. In animals, including humans, the anaerobic cycle produces lactic acid, which causes muscle cramps.
d. The fermentation process in anaerobic respiration is roughly 5 percent as effective as what cells can do when they have access to oxygen.
e. In bacteria, it may produce nitrite, nitrogen gas, hydrogen sulfide, methane and acetic acid.
Answer (c, d and e). "Anaerobic" means without oxygen, and respiration refers to the processes in a cell that convert biochemical energy, such as that found in glucose, into usable energy in the form of ATP. Waste products like carbon dioxide are also produced during this process.
The fermentation process in anaerobic respiration is roughly 5 percent as effective as what cells can do when they have access to oxygen. An aerobic cycle may produce between 36 and 38 ATP molecules, while anaerobic respiration only creates 2 ATP molecules.
Since muscles often run out of oxygen during extreme exertion, anaerobic respiration keeps them running. In animals, including humans, the anaerobic cycle produces lactic acid, which causes muscle cramps. In order for these cramps to stop, oxygen must find its way back into the muscle again so these cells can switch back to aerobic respiration and stop building up lactic acid.
Anaerobic respiration is also common in bacteria that live in environments without oxygen; depending on the bacteria, the products of their respiration include nitrite, nitrogen gas, hydrogen sulfide, methane and acetic acid.
19. Which of the following best describes the Capitation System?
a. Risk free income for healthcare service providers.
b. Healthcare provider may get more incentive to provide an extended treatment to a patient.
c. A fixed amount of money per patient per unit of time paid in advance to the physician for the delivery of health care services.
d. A patient gets more benefit if he/she gets services from Healthcare provider receiving reimbursement through capitation.
e. Free prescription benefits to patients.
Answer: Capitation payments are used by managed care organizations to control health care costs. Capitation payments control use of health care resources by putting the physician at financial risk for services provided to patients. At the same time, in order to ensure that patients do not receive suboptimal care through under-utilization of health care services, managed care organizations measure rates of resource utilization in physician practices. These reports are made available to the public as a measure of health care quality, and can be linked to financial rewards, such as bonuses.
Capitation is a fixed amount of money per patient per unit of time paid in advance to the physician for the delivery of health care services. The actual amount of money paid is determined by the ranges of services that are provided, the number of patients involved, and the period of time during which the services are provided. Capitation rates are developed using local costs and average utilization of services and therefore can vary from one region of the country to another. In many plans, a risk pool is established as a percentage of the capitation payment. Money in this risk pool is withheld from the physician until the end of the fiscal year. If the health plan does well financially, the money is paid to the physician; if the health plan does poorly, the money is kept to pay the deficit expenses.
When the primary care provider signs a capitation agreement, a list of specific services that must be provided to patients is included in the contract. The amount of the capitation will be determined in part by the number of services provided and will vary from health plan to health plan, but most capitation payment plans for primary care services include the following:
· Preventive, diagnostic, and treatment services
· Injections, immunizations, and medications administered in the office
· Outpatient laboratory tests done either in the office or at a designated laboratory
· Health education and counseling services performed in the office
· Routine vision and hearing screening
20. Which of the following information is/are TRUE ABOUT Essential Fatty Acids? [Select ALL That Apply]
a. Linoleic and alpha-linolenic are essential fatty acids.
b. Arachidonic acid is classified as ‘conditionally essential’ fatty acid.
c. Ideally, in the diet, the ratio of omega-6 to omega-3 fatty acids should be between 1:1 and 4:1.
d. Excessive intake of omega-6 fatty acids can cause the deficiency of omega-3 fatty acids.
Answer (a, b, c and d). Essential fatty acids, or EFAs, are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them.
Only two fatty acids are known to be essential for humans: alpha-linolenic acid (an omega-3 fatty acid) and linoleic acid (an omega-6 fatty acid). Some other fatty acids are sometimes classified as "conditionally essential," meaning that they can become essential under some developmental or disease conditions; examples include docosahexaenoic acid and gamma-linolenic acid.
It is not only important to incorporate good sources of omega-3 and omega-6s in a diet, but also consume these fatty acids in the proper ratio. Omega-6 fatty acids compete with omega-3 fatty acids for use in the body, and therefore excessive intake of omega-6 fatty acids can inhibit the use of omega-3 fatty acids by the body.
Ideally, the ratio of omega-6 to omega-3 fatty acids should be between 1:1 and 4:1. Instead, most Americans consume these fatty acids at a ratio of omega-6: omega-3 between 10:1 and 25:1, and are consequently unable to reap the benefits of omega-3s.
This imbalance is due to a reliance on processed foods and oils, which are now common in the Western diet. To combat this issue it is necessary to eat a low-fat diet with minimal processed foods and with naturally occurring omega-3 fatty acids. A lower omega-6: omega-3 ratio is desirable for reducing the risk of many chronic diseases.
Arachidonic acid is not one of the essential fatty acids. However, it does become essential if there is a deficiency in linoleic acid or if there is an inability to convert linoleic acid to arachidonic acid.
21. Which of the following is/are Type(s) of Refractive Errors? [Select All That Apply]
a. myopia
b. hyperopia
c. Astigmatism
d. Presbyopia
a. a only
b. a and b only
c. a, b and c only
d. a, b, c and d
Answer: (d) All. Refractive errors happen when the shape of your eye keeps light from focusing correctly on your retina (a light-sensitive layer of tissue at the back of your eye).
Each type of refractive error is different, but they all make it hard to see clearly.
Nearsightedness (myopia):
Nearsightedness makes far-away objects look blurry. It happens when the eyeball grows too long from front to back, or when there are problems with the shape of the cornea (clear front layer of the eye) or the lens (an inner part of the eye that helps the eye focus). These problems make light focus in front of the retina, instead of on it.
Nearsightedness usually starts between ages 6 and 14. Children who spend more time outdoors during these years are less likely to develop nearsightedness, but experts aren’t sure why.
Severe nearsightedness (also called high myopia) can increase the risk of other eye conditions, like retinal detachment (when the retina is pulled away from its normal position).
Farsightedness (hyperopia):
Farsightedness makes nearby objects look blurry. It happens when the eyeball grows too short from front to back, or when there are problems with the shape of the cornea or lens. These problems make light focus behind the retina, instead of on it.
People with farsightedness are usually born with it.
Astigmatism:
Astigmatism can make far-away and nearby objects look blurry or distorted. It happens when the cornea or lens has a different shape than normal, which makes light bend differently as it enters the eye.
Some people with astigmatism are born with it, but many people develop it as children or young adults. People with astigmatism often have another refractive error, like nearsightedness or farsightedness.
Presbyopia:
Presbyopia makes it hard for middle-aged and older adults to see things up close. As you age, the lens in your eye gets harder and less flexible and stops focusing light correctly on the retina.
Everyone gets presbyopia as they get older, usually after age 45. Many people have another refractive error in addition to presbyopia.
Source: www.pharmacyexam.com
Citation: https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/refractive-errors/types-refractive-errors
22. Which of the following types of glaucoma is NOT CONSIDERED a primary glaucoma?
a. Open-angle
b. Congenital
c. Pigmentary
d. Angle-closure
Answer: (c). Glaucoma is a group of eye diseases that are usually characterized by damage to the optic nerve and gradual vision loss that starts with losing peripheral (side) vision. People who have high eye pressure are at higher risk for glaucoma.
Primary glaucomas:
When experts don’t know what causes a type of glaucoma, that type is called a primary glaucoma.
Pigmentary glaucoma is considered secondary glaucoma.
1. Open-angle glaucoma
Treatments: Medicines, laser treatment, surgery
Open-angle glaucoma is the most common type in the United States, where 9 in 10 people with glaucoma have the open-angle type. Many people don’t have any symptoms until they start to lose their vision, and people may not notice vision loss right away.
Experts aren’t sure what causes open-angle glaucoma, but it may be caused by pressure building up in your eye. If the fluid in your eye can’t drain fast enough, it creates pressure that pushes on a nerve in the back of your eye (the optic nerve).
Over time, the pressure damages the optic nerve, which affects your vision. This can eventually lead to blindness — in fact, open-angle glaucoma causes almost 2 in 10 cases of blindness in African Americans. People with high blood pressure are also at higher risk for this type.
2. Normal-tension glaucoma
Treatments: Medicines, laser treatment, surgery
Normal-tension glaucoma is a type of open-angle glaucoma that happens in people with normal eye pressure. About 1 in 3 people with open-angle glaucoma have the normal-tension type.
You may be at higher risk for normal-tension glaucoma if you:
23. _______________ glaucoma happens when the eye makes extra blood vessels that cover the part of your eye where fluid would normally drain.
a. Neovascular
b. Pigmentary
c. Exfoliation
d. Uveitic
Answer: (a). Glaucoma is a group of eye diseases that are usually characterized by damage to the optic nerve and gradual vision loss that starts with losing peripheral (side) vision. People who have high eye pressure are at higher risk for glaucoma.
Primary glaucomas:
When experts don’t know what causes a type of glaucoma, that type is called a primary glaucoma.
Secondary glaucomas:
Sometimes glaucoma is caused by another medical condition — this is called secondary glaucoma.
1. Neovascular glaucoma
Treatments: Medicines, laser treatment, surgery
Neovascular glaucoma happens when the eye makes extra blood vessels that cover the part of your eye where fluid would normally drain. It’s usually caused by another medical condition, like diabetes or high blood pressure.
If you have neovascular glaucoma, you may notice:
24. Pharmacists should be able to recognise red flag signs of Postnatal depression (PND) and refer these patients immediately. Which of the following is/are Red flag signs or symptoms for postnatal depression?
I. Recent significant change in mental state or emergence of new psychiatric symptoms
II. New thoughts or acts of violent self-harm.
III. New and persistent expressions of incompetency as a mother, such as being over-critical for not recognising what the baby needs.
a. I only
b. I and II only
c. II and III only
d. All
Answer: (d). All. Pharmacists should be able to recognise red flag signs and symptoms of PND and refer these patients immediately.
Red flag signs for postnatal depression:
25. Which of the following is a genetic condition in which abnormal growth of the heart muscle fibers occurs, leading to the thickening of these fibers?
a. Dilated cardiomyopathy
b. Hypertrophic cardiomyopathy
c. Restrictive cardiomyopathy
d. Arrhythmogenic cardiomyopathy
Answer: (b). Hypertrophic cardiomyopathy.
1. Dilated cardiomyopathy: Dilated cardiomyopathy is the most common form of the disease. It typically occurs in adults between the ages of 20 and 60 years.
The disease often starts in the left ventricle, but it can eventually also affect the right ventricle.
Dilated cardiomyopathy can affect the structure and function of the atria, too.
2. Hypertrophic cardiomyopathy:
Hypertrophic cardiomyopathy is a genetic condition in which abnormal growth of the heart muscle fibers occurs, leading to the thickening or "hypertrophy" of these fibers. The thickening makes the chambers of the heart stiff and affects blood flow. It can also increase the risk of electrical disturbances, called arrhythmias.
According to the Children's Cardiomyopathy Foundation, it is the second most common form of cardiomyopathy in children. In about one-third of affected children, diagnosis occurs before the age of 1 year.
3. Restrictive cardiomyopathy:
Restrictive cardiomyopathy occurs when the tissues of the ventricles become rigid and cannot fill with blood properly. Eventually, it may lead to heart failure. It is more common in older adults and can result from infiltrative conditions — those involving the accumulation of abnormal substances in bodily tissues — such as amyloidosis.
4. Arrhythmogenic cardiomyopathy:
In arrhythmogenic cardiomyopathy, fibrotic and fatty tissue replaces the healthy tissues of the right ventricle, which may cause irregular heart rhythms. In some cases, this process can also occur in the left ventricle.
According to research in the journal Circulation Research, arrhythmogenic cardiomyopathy increases the risk of sudden cardiac death, especially in young people and athletes. It is a hereditary genetic condition.
Symptoms:
In some cases, usually mild ones, there are no symptoms of cardiomyopathy.
However, as the condition progresses, a person may experience the following symptoms with varying degrees of severity:
26. Which of the following information is/are TRUE ABOUT Oscillopsia? [Select All That Apply]
a. It is the sensation that the surrounding environment is constantly in motion when it is, in fact, stationary.
b. It is usually a symptom of conditions that affect eye movement or the eye's ability to stabilize images, especially during movement.
c. It often links to types of ataxia, which is a condition that causes abnormal or involuntary eye movement.
d. The American Psychological Association describe oscillopsia as "the sensation of perceiving oscillating movement of the environment."
e. It is usually associated with neurological conditions, such as multiple sclerosis.
Answer: (a, b, d and e).
Oscillopsia is the sensation that the surrounding environment is constantly in motion when it is, in fact, stationary. It usually occurs as a result of conditions that affect eye movement or alter how parts of the eye, inner ear, and brain stabilize images and maintain balance. The American Psychological Association describe oscillopsia as "the sensation of perceiving oscillating movement of the environment."
It often links to types of nystagmus (not ataxia), which is a condition that causes abnormal or involuntary eye movement.
Some of the most common conditions that experts have associated with oscillopsia include:
1. neurological conditions, such as seizures, multiple sclerosis, and superior oblique myokymia
2. brain or head injuries, especially bilateral vestibular cerebellar injuries
3. conditions, such as stroke, that affect the eye muscles or muscles around the eyes
4. conditions that affect or damage the inner ear, including Meniere's disease
5. conditions that cause brain inflammation, such as tumors or meningitis
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