Page 8 - RxExam's Naplex Theory Book Part II

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Dose Special Notes

Finasteride 4). Finasteride, under the brand name of Propecia, is indicated for the
(Tablet) treatment of male pattern hair loss (androgenetic alopecia) in MEN
ONLY. It must NOT be used in children or women.

5). Women should NOT handle crushed or broken Finasteride (Proscar)
tablets when they are pregnant or may potentially be pregnant
because of the possibility of absorption of Finasteride (Proscar) and
the subsequent potential risk to a male fetus. Finasteride (Proscar)
tablets are coated and will prevent contact with the active ingredient
during normal handling, provided that the tablets have not been
broken or crushed.

6). Finasteride (Proscar) is classified under pregnancy category X.

Dutasteride 1). B.P.H. 1). Dutasteride (Avodart) is a synthetic 4-azasteroid compound that is
(Capsule) a selective inhibitor of both the type 1 and type 2 isoforms of steroid 5
a). Avodart alpha-reductase, an intracellular enzyme that converts testosterone to
0.5 mg taken once DHT.
daily with or
without food. 2). Dutasteride (Avodart) is indicated for the treatment of
symptomatic benign prostatic hyperplasia (BPH) in men with an
b). Jalyn enlarged prostate to:
0.5 mg Dutasteride, i). improve symptoms,
0.4 mg Tamsulosin ii). reduce the risk of acute urinary retention (AUR), and
once daily with or iii). reduce the risk of the need for BPH-related surgery.
without food.
3). In combination with the alpha adrenergic antagonist, Tamsulosin, it
(Jalyn) is indicated for the treatment of symptomatic BPH in men with
an enlarged prostate.

4). The capsules of Dutasteride (Avodart) should be swallowed whole
and not chewed or opened, as contact with the capsule contents may
result in irritation of the oropharyngeal mucosa.

5). Dutasteride (Avodart) capsules should NOT be handled by a woman
who is pregnant or who could become pregnant. Dutasteride
(Avodart) is absorbed through the skin and could result in unintended
fetal exposure. If a woman who is pregnant or who could become
pregnant comes in contact with leaking dutasteride capsules, the
contact area should be washed immediately with soap and water. It is
classified under pregnancy category X.

6). Impotence, decreased libido, breast disorders (including breast
enlargement and tenderness), dizziness and ejaculation disorders are
most commonly reported side effects of Dutasteride (Avodart).

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