Page 46 - Naplex Q&A 2025 Version

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Do not use Foradil Aerolizer for patients whose In osteoarthritis, rheumatoid arthritis, and
asthma is adequately controlled on low or medium ankylosing spondylitis, the recommended starting
dose inhaled corticosteroids. dosage is 150 mg twice a day. The dosage may be
lowered or raised depending on the response.
Proventil (Albuterol), Brethaire (Terbutaline),
Maxair (Pirbuterol) and Tornalate (Bitolterol) are In acute painful shoulder (acute subacromial
classified as short acting beta-2 receptor agonists. bursitis/supraspinatus tendinitis) and acute gouty
They are indicated for the treatment of acute arthritis, the recommended dosage is 200 mg twice
symptoms of asthma. a day. In acute painful shoulder, therapy for 7 to 14
days is usually adequate. In acute gouty arthritis,
44.(c) All of the above mentioned NSAIDs can be therapy for 7 days is usually adequate.
used for the treatment of pain. But the patient has
a habit of forgetting things. The most frequent types of adverse reactions
occurring with Sulindac (Clinoril) are
Feldene (Piroxicam) is classified as a nonsteroidal gastrointestinal; these include gastrointestinal pain
anti-inflammatory agent. It is indicated for the (10%), dyspepsia, nausea with or without vomiting,
treatment of mild to moderate pain. It can be taken diarrhea, constipation, flatulence, anorexia and
twice daily because of its prolonged duration of gastrointestinal cramps.
action and extended half-life, and so it is more
appropriate for the treatment of pain in Chris. 46. (c) Naprosyn, Anaprox, and Anaprox DS
(Naproxen) are classified as NSAIDs. Naproxen is
The recommended daily dose of Piroxicam is 20 mg indicated for the treatment of mild to moderate
per day in a single or two divided doses. Ulcer, G.I. pain associated with rheumatoid arthritis,
bleeding, nausea and vomiting are reported side osteoarthritis, ankylosing spondylitis,
effects of the drug. dysmenorrhea, acute tendonitis and bursitis.
It is available in tablet and oral suspension forms.
45.(c) Sulindac (Clinoril) is a prodrug, derived from The recommended dose of Naproxen is 500 mg to
sulfinylindene, that is converted in the body to the 1000 mg per day in two to three divided doses. G.I.
active NSAID. It is available in 200 mg tablets for ulceration and bleeding are reported side effects of
oral administration. Following absorption, Sulindac the drug.
(Clinoril) undergoes two major biotransformations -
reversible reduction to the sulfide metabolite, and 47.(b) The normal therapeutic serum concentration
irreversible oxidation to the sulfone metabolite. range for Dilantin should be between 10 and 20
Available evidence indicates that the biological mcg/ml. The serum concentration greater than 20
activity resides with the sulfide metabolite. mcg/ml may cause nystagmus whereas the serum
concentration greater than 30 mcg/ml may cause
Sulindac (Clinoril) is indicated for acute or long-term ataxia. The serum concentration above 40mcg/ml
use in the relief of signs and symptoms of the may cause lethargy and dysarthria.
following: Osteoarthritis, Rheumatoid arthritis,
Ankylosing spondylitis, Acute painful shoulder 48. (a,d) Noxafil (Posaconazole) is a triazole
(Acute subacromial bursitis/supraspinatus antifungal agent available in a suspension for an
tendinitis) and Acute gouty arthritis. oral administration, injection and delayed release
tablet dosage forms. The oral suspension is a white,
Sulindac (Clinoril) should be administered orally cherry-flavored immediate-release suspension
twice a day with food. The maximum dosage is 400 containing 40 mg of Posaconazole per ml.
mg per day. Dosages above 400 mg per day are not
recommended. It is indicated for prophylaxis of invasive Aspergillus
and Candida infections in patients, 13 years of age

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