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Also, Digoxin suppresses A.V. node conduction. (not the hypertension) being treated with
Diltiazem and Verapamil have negative effects on levodopa/carbidopa who exhibit deterioration in
A.V. node conduction which result in bradycardia the quality of their response to the therapy.
when used concurrently with Digoxin.
The normal serum concentration of Digoxin should Treatment should be initiated with 1.25 mg given
lie between 0.7 and 1.4 ng/ml. It is available as once a day for at least 6 weeks. After 6 weeks, the
tablet, capsule, elixir and injection. dose may be escalated to 2.5 mg given once a day if
a desired benefit has not been achieved and the
It is indicated for the treatment of congestive heart patient is tolerating Zelapar. It should be taken in
failure (CHF). The recommended dose is 0.125mg to the morning before breakfast and without liquid.
0.375mg by mouth per day.
A severe hypertensive crisis, orthostatic/postural
13.(b) Corgard (Nadolol) is classified as a beta hypotension, dizziness, somnolence, ECG
blocker. It is indicated for the treatment of abnormality, nausea, dyspepsia, abnormal dreams,
hypertension and angina. and infection are reported side effects of Zelapar.

The recommended therapeutic dose of the drug is 15.(a) Claritin (Loratadine), Clarinex
40 to 80 mg once a day. It is prescribed for (Desloratadine), Allegra (Fexofenadine) and Zyrtec
excessively high doses - 80mg four times a day. (Cetirizine) are classified as non-sedative
Because of its prolonged duration of action and long antihistamines. The non-sedative action of this class
half-life, it is generally recommended in a single of antihistamines is attributed to their inability to
daily dose. cross the Blood Brain Barrier (B.B.B).

Beta blockers have a suppression effect on A.V. Claritin (Loratadine) is available as tablets, syrup
node conduction, and therefore caution is required and rapidly-disintegrating tablets (RediTabs). Each
when used simultaneously with calcium-channel tablet for an oral administration contains 10 mg
blockers like Diltiazem and Verapamil. Loratadine as an active ingredient. It is indicated for
the relief of nasal and non-nasal symptoms of
Beta blockers may mask the symptoms of seasonal allergic rhinitis and for the treatment of
hypoglycemia such as tachycardia; confusion, chronic idiopathic urticaria in patients 2 years of age
difficulty in concentration, and therefore their use or older.
require great caution in diabetic patients. They also
impair the gluconeogenesis and thereby prolong For adults and children 6 years of age and over, the
the period of hypoglycemia. recommended dose of Claritin is one 10 mg tablet
or Reditab, or 2 teaspoonfuls (10 mg) of syrup once
Beta blockers should never be used by the patient daily. For children 2 to 5 years of age, the
suffering from congestive heart failure (CHF). recommended dose of Claritin syrup is 5 mg (1
Acebutolol, Atenolol, Metoprolol and Betaxolol are teaspoonful) once daily.
cardio-selective beta-blockers.
All other choices indicate antihistamines that have
14.(e) Zelapar orally disintegrating tablets contain sedation property. Chlor-Trimeton
Selegiline hydrochloride as an active ingredient. (Chlorpheniramine), Benadryl (Diphenhydramine),
Dimetane (Brompheniramine) and Unisom
Selegiline is best known as an irreversible inhibitor (Doxylamine) are classified as sedative
of monoamine oxidase (MAO). It is available for oral antihistamines.
administration (not to be swallowed) in a strength
of 1.25 mg. It is indicated as an adjunct in the 16. (c) Lucentis (Ranibizumab injection) is a
management of patients with Parkinson’s disease recombinant monoclonal antibody designed for

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