Page 20 - FPGEE Medicinal and Organic Chemistry Q&A Book

Krisman

270. Below is the structure of Cidofovir a. Acyclovir
(Vistide). It is a nucleotide analogue of cytosine b. Griseofulvin
where cytosine is classified as: c. Idoxuridine
d. Penciclovir
NH
2
273. The name of heterocyclic aromatic com-
N
pound present in Ribavirin is:
O N O
N
CH 2 O C NH 2
H O
CH O CH 2 P OH
O N N
OH
CH OH
2
Cidofovir
H O OH
a. Pyrimidine base
Ribavirin
b. Purine base
c. Indole base a. Phenol
d. Pyrrole base b. Triazole
c. Pyrazole
271. The compound shown below may cause: d. Benzoic acid

O 274. Below is the structure of the very well
- - + known anti-HIV drug Zidovudine. Please
COO P O Na
3 identify heterocyclic, aliphatic and organic func-
- tional groups in it.
O
O
a. Severe hypotension CH 3
b. Seizure H N
c. Electrolyte disturbances
O N
d. Severe nausea and vomiting
O
H O CH 2
272. Below is the structure of antiviral drug
Famciclovir. It is a prodrug of:
N 3
Zidovudine
N
N
I. Tetrahydrofuran
N
NH N II. Thymidine
2
CH 3 COO CH 2 III. Azido
CH CH CH
2 2
a. I only
CH COO CH
3 2
b. I and II only
Famciclovir c. II and III only
d. All

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