Page 19 - FPGEE Medicinal and Organic Chemistry Q&A Book
P. 19

Krisman



               263.    The  compound  shown  below  is           c.     Capecitabine
               classified as:                                    d.     Thioguanine

                                    O
                                                                 268.   The compound shown below is pharma-
                      CH   CH   N   C   NH   CH   CH
                         2    2                2    2            cologically and structurally related to:
                    Cl          NO                  Cl
                                                                                NH   CH
                                                                                   2    3
                                                                                    CH
               a.      Nitrogen mustard
               b.      Triazenes
               c.      Nitrosoureas
               d.      Mitosis inhibitor


               264.    The compound shown below is known
               as:                                               a.     Metoprolol
                                                                 b.     Nifedipine
                       O  CH 2  CH 2  CH 2  CH 2  O
                                                                 c.     Amantadine
                    CH SO                         CH SO
                       3   2                        3   2        d.     Diphenhydramine

               a.      Cisplatin                                 269.   Below is the structure of the well known
               b.      Dacarbazine                               antiviral drug acyclovir.  What is the name of
               c.      Chlorambucil                              the heterocyclic organic compound present in
               d.      Busulfan                                  the structure?
                                                                                    O
               265.    What is the backbone structure of Doxo-
                                                                                            N
               rubicin?                                                        HN

               a.      Sulfonamide                                           NH 2   N       N
               b.      Tetracycline
                                                                          H O      CH 2     CH 2
               c.      Anthracyclins                                           CH 2     O
               d.      Phenylhydrazine
                                                                                 Acyclovir

               266.    Which of the following free radicals pro-  a.    Guanine
               duced by anthracycline antibiotics may induce     b.     Adenine
               severe irreversible cardiac tissue damage?        c.     Cytosine
                                                                 d.     Uracil
               a.      H O  +
                        3
               b.      .OH
               c.      .O   -
                         2
               d.      Fe  +2


               267.    Which of the following is NOT a pyri-
               midine antagonist?

               a.      Fluorouracil
               b.      Methotrexate



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