Page 14 - FPGEE Medicinal and Organic Chemistry Q&A Book

Krisman

234. The chances of methemoglobinemia and 237. In the following structure, please
hemolytic anemia are higher when identify the major functional group.
administering:
CH 3
CH COOH
I. Acetaminophen
O
II. Phenacetin
C
III. Acetanilide

a. I only
Ketoprofen
b. I and II only
c. II and III only a. Ether
d. All b. Ester
c. Ketone
235. The structure shown below is known as: d. Phenol

CO-NH 2 238. Below is the structure of probenecid.
Which of the following statements are TRUE if
we replace both (C H ) groups at the nitrogen
7
3
OH position with (CH ) groups?
3
a. acetyl salicylic acid C H O
3 7
b. salicylsalicylic acid
N S COOH
c. salicylamide
d. 5-(2,4-difluorophenyl)-salicyclic acid C H O
3 7
Probenecid
236. What is the name of the functional aro-
matic group in nabumetone? I. Uricosuric activity decreases with the
O substitution of methyl groups.
CH C
2
CH 3 II. Renal clearance of the compound de-
CH
2 creases with substitution of methyl groups.
OCH 3
Nabumetone III. The reabsorption of uric acid in proxi-
mal tubules increases with substitution of me-
a. naphthalene thyl groups.
b. phenanthrene
c. pentacene a. I only
d. benzopyrene b. I and II only
c. II and III only
d. All

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