According to Florida Pharmacy Law, which of the following is/are included in a negative drug formulary?
I. Theophylline
II. Conjugated estrogen
III. Dicumarol
a. I only
b. I and II only
c. II and III only
d. All
Answer: d
The negative drug formulary is composed of medicinal drugs which have been specifically determined by the Florida Board of Pharmacy and the Board of Medicine to demonstrate clinically significant biological or therapeutic inequivalence and which, if substituted, could produce adverse clinical effects, or could otherwise pose a threat to the health and safety of patients receiving such prescription medications. The following are included on the negative drug formulary:
(1). Digitoxin.
(2). Conjugated Estrogen.
(3). Dicumarol.
(4). Chlorpromazine (Solid Oral Dosage Forms).
(5). Theophylline (Controlled Release).
(6). Pancrelipase (Oral Dosage Forms).
Substitution by a dispensing pharmacist on a prescription written for any brand name equivalent of a generic named drug product listed on the negative formulary or for a drug within the class of certain dosage forms as listed, is strictly prohibited.
In cases where the prescription is written for a drug listed on the negative drug formulary but a brand name equivalent is not specified by the prescriber, the drug dispensed must be one obtained from a manufacturer or distributor holding an approved new drug application or abbreviated new drug application issued by the Food and Drug Administration, United States Department of Health and Welfare permitting that manufacturer or distributor to market those medicinal drugs or when the former is non-applicable, those manufacturers or distributors supplying such medicinal drugs must show compliance with other applicable Federal Food and Drug Administration marketing requirements.