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Thiazide diuretics should NOT be used as a first line treatment for hypertension in patient suffering from:

a. Hyperlipidemia
b. Heart failure
c. COPD
d. Gout
e. Peripheral artery disease

Answer :(d). Thiazide diuretics may increase the reabsorption of uric acid from renal tubules and may cause hyperuricemia. It should NOT be used as a first line treatment for hypertension in patient suffering from gout.

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