Page 11 - Pharmacy Technician Book

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3. Beta-Blockers

M/A: They block Beta-1 receptors in cardiac tissues. They reduce the oxygen requirement of the
heart by decreasing the heart rate and force of contraction of the heart associated with an exercise.

Brand Generic Adverse Effects

Tenormin Atenolol Bradycardia

Lopressor, Toprol XL Metoprolol Bradycardia

Inderal Propranolol Bradycardia

Corgard Nadolol Bradycardia

Zebeta Bisoprolol Bradycardia

Normodyne, Trandate Labetalol Bradycardia

Sectral Acebutolol Bradycardia

Coreg Carvedilol Bradycardia

Brevibloc Esmolol Bradycardia

Levatol Penbutolol Bradycardia

Therapeutic Use(s):

 Hypertension and angina

Do not use beta-blockers for:

 CHF patients: May cause fatal heart failure.
 Diabetic patients: May mask the symptoms of hypoglycemia.
 Asthma patients: May constrict the bronchial smooth muscles by blocking beta-2 receptors.

Terminology

 Bradycardia: Slowing down of heart rate.
 Hypoglycemia: Low blood glucose level.
 Bronchial muscles: Smooth muscles of lungs.
 Angina: Heart disorder with sharp pain in heart.

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