Page 65 - Naplex Q&A 2025 Version

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The recommended dose of Zaroxolyn is 5 to 20 once 263 mg, 350 mg, and 525 mg of paliperidone,
daily for the treatment of an edema of cardiac or respectively.
renal failure, and 2.5 to 5 mg once daily for the
treatment of mild to moderate essential Invega-Trinza (Paliperidone palmitate), a 3-month
hypertension. injection, is indicated for the treatment of
schizophrenia in patients after they have been
Hypokalemia, hypotension, electrolyte loss, adequately treated with Invega-Sustenna (1-month
hyperuricemia, hypomagnesemia, hyponatremia paliperidone palmitate extended-release injectable
and hyperglycemia are reported side effects of the suspension) for at least four months.
drug.
It is important to shake the syringe vigorously for at
133.(e) The active ingredient found in Tornalate is least 15 seconds to ensure a homogeneous
Bitolterol mesylate. It is a prodrug which is suspension. Inject Invega-Trinza within 5 minutes of
hydrolyzed by tissue esterase enzymes in lung shaking vigorously.
tissues to, an active moiety, Colterol.
Dementia related psychosis, QT prolongation,
It is classified as a short-acting Beta-2 receptors tardive dyskinesia, NMS, orthostatic hypotension
agonist. It is indicated for the treatment of asthma. and syncope are reported side effects of Invega-
For the treatment of an acute bronchospasm in Trinza.
adults and children older than 12 years of age, the
recommended dose is 2 inhalations by mouth at 136.(e) The principal advantage of Tornalate over
interval of 1 to 3 min, followed by third inhalation if the other bronchodilators is its prolonged duration
necessary. of action compared to other short-acting Beta-2
agonists. The duration of action of Tornalate is 5
For the prevention of bronchospasm in adults and hours in most of the patients, while 8 or more hours
children older than 12 years of age, the have been reported in a few of the patients.
recommended dose is 2 inhalations every 8 hours,
not to exceed 3 inhalations every 6 hours or 2 137.(c) Because of its prolonged duration of action,
inhalations every 4 hours. the recommended dose of Tornalate would be 2
inhalations every 8 hours. The doses of Tornalate
134.(a) Aciphex (Rabeprazole) is classified as a should never exceed 12 inhalations per day. The
proton pump inhibitor. It is indicated for the prescribed dose is too high.
treatment of duodenal ulcers, erosive or ulcerative
GERD, and Zollinger-Ellison syndrome. It is available 138.(d) Invega Sustenna is an extended-release
for oral administration as delayed-release, enteric- injectable formulation of Paliperidone administered
coated tablets containing 20 mg of Rabeprazole once-monthly for the acute and maintenance
sodium. Aciphex Sprinkle is available for oral treatment of schizophrenia.
administration as 5 mg and 10 mg Rabeprazole
sodium delayed-release capsules containing enteric Recommended initiation of Invega Sustenna is with
coated granules. The recommended dose is 20 mg a dose of 234 mg on treatment day 1 and 156 mg
once daily for at least 4 to 8 weeks. Headache and one week later, both administered in the deltoid
diarrhea are two most common adverse effects muscle. The recommended monthly maintenance
reported with the drug. dose is 117 mg; some patients may benefit from
lower or higher maintenance doses within the
135.(a,b,d,e) Invega-Trinza, an antipsychotic recommended range of 39 to 234 mg based on
agent, is available as a white to off-white sterile individual patient tolerability and/or efficacy.
aqueous extended-release suspension for
intramuscular injection in dose strengths of 175 mg,

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