Page 53 - Naplex Q&A 2025 Version

www.pharmacyexam.com

16 mg per day. The usual maintenance dose range is of citric acid. The recommended dose of
4 mg to 8 mg administered as a single daily dose or Acetaminophen is 325 to 650 mg every 4 to 6 hours
in two divided doses. as needed. Liver toxicity is the principal side effect
of the drug.
Chest pain, hypotension, dry cough, rash,
hyperkalemia, dizziness and myalgia are reported 80. (d) These symptoms indicate dystonic reaction,
side effects of the drug. which involves sudden spasm of the neck, face or
trunk. Dystonic reaction can be managed by
78. (b,c,d) Risperdal (Risperidone) is classified as an anticholinergic agents like Benadryl
antipsychotic agent. It is available in tablet (0.25, (Diphenhydramine) or Cogentin (Benztropine).
0.5, 1, 2, 3 and 4-mg), oral solution (1mg/ml), long-
acting injection (Risperdal Consta: 12.5, 25, 37.5 For the treatment of akathisia, Valium (Diazepam)
and 50-mg) and orally disintegrating tablet (0.5, 1, and anticholinergic agents are usually preferable.
2, 3 and 4-mg).
For the treatment of drug-induced Parkinson’s,
Risperdal (Risperidone) is indicated for the anticholinergic drugs have been found effective.
treatment of:
81. (a,c,d,e) Clozaril (Clozapine) is classified as an
1. Schizophrenia atypical antipsychotic agent. It is indicated for the
2. As monotherapy or as adjunctive therapy to treatment of severely ill patients with schizophrenia
lithium or valproate for the maintenance treatment who fail to respond adequately to standard
of Bipolar I Disorder antipsychotic treatment. Because of the risks of
3. Acute manic or mixed episodes associated with severe neutropenia (Agranulocytosis) and of seizure
Bipolar I Disorder. associated with its use, Clozaril (Clozapine) should
4. Irritability associated with autistic disorder, be used only in patients who have failed to respond
including symptoms of aggression towards others, adequately to standard antipsychotic treatment.
deliberate self-injuriousness; temper tantrums, and
quickly changing moods. Prior to initiating treatment with Clozaril, a baseline
ANC must be obtained. The baseline ANC must be
The dosage of Risperdal should be individualized at least 1500/µL for the general population, and at
according to the response and tolerability of the least 1000/µL for patients with documented Benign
patient. The total daily dose of Risperdal can be Ethnic Neutropenia (BEN). To continue treatment,
administered once daily or half the total daily dose the ANC must be monitored regularly.
can be administered twice daily.
The starting dose is 12.5 mg once daily or twice
Caution should be exercised with dosage for smaller daily. The total daily dose can be increased in
children who weigh less than 15 kg. NMS, tardive increments of 25 mg to 50 mg per day, if well-
dyskinesia, extrapyramidal symptoms and agitation tolerated, to achieve a target dose of 300 mg to 450
are reported side effects of the drug. mg per day (administered in divided doses) by the
end of 2 weeks. Subsequently, the dose can be
79. (e) Bromo Seltzer (Effervescent granules of increased once weekly or twice weekly, in
Acetaminophen) is classified as an analgesic and increments of up to 100 mg.
antipyretic agent. It is indicated for relieving pain
and fever associated with various disease The maximum dose is 900 mg per day. To minimize
conditions. the risk of orthostatic hypotension, bradycardia,
and syncope, it is necessary to use this low starting
Bromo Seltzer contains 325 mg of Acetaminophen dose, gradual titration schedule, and divided
with 2.781 gm of sodium bicarbonate and 2.224 gm dosages. It can be taken with or without food.

218