Page 52 - Naplex Q&A 2025 Version

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73.(d) The active ingredients found in Advair Diskus 75. (a,b,d) FazaClo, Clozaril and Versacloz are brand
are Flovent (Fluticasone) and Serevent (Salmeterol). names for generic Clozapine. FazaClo is available as
12.5 mg orally disintegrating tablet. Clozaril is
Serevent (Salmeterol) is a long-acting β2-adrenergic available as 25mg tablet whereas Versacloz is
bronchodilator whereas Flovent (Fluticasone) is a available as a free-flowing yellow oral suspension.
glucocorticosteroid. Each mL contains 50 mg of clozapine. Clozapine is
indicated for the treatment of schizophrenia.
Long-acting beta2-adrenergic agonists (LABA), such
as Salmeterol, one of the active ingredients in 76. (e) Brovana (Arformoterol tartrate) is a selective
Advair Diskus, increase the risk of asthma-related long-acting beta2-adrenergic bronchodilator. It is
death. indicated for the long term, twice daily (morning
and evening) maintenance treatment of
Therefore, when treating patients with asthma, bronchoconstriction in patients with chronic
physicians should only prescribe Advair Diskus for obstructive pulmonary disease (COPD), including
patients not adequately controlled on a long-term chronic bronchitis and emphysema.
asthma control medication, such as an inhaled
corticosteroid, or whose disease severity clearly Long-acting beta2-adrenergic agonists (LABA), such
warrants initiation of treatment with both an as Arformoterol, an active ingredient found in
inhaled corticosteroid and a LABA. Brovana, increase the risk of asthma-related death.

Once asthma control is achieved and maintained, Once asthma control is achieved and maintained,
assess the patient at regular intervals and step assess the patient at regular intervals and step
down therapy (e.g., discontinue Advair Diskus) if down therapy (e.g., discontinue Brovana) if possible
possible without loss of asthma control and without loss of asthma control and maintain the
maintain the patient on a long-term asthma control patient on a long-term asthma control medication,
medication, such as an inhaled corticosteroid. such as an inhaled corticosteroid.

It is indicated for the treatment of asthma in It is for use by nebulization only. The recommended
patients aged 4 years and older. It should not be dose of Brovana (Arformoterol tartrate) inhalation
used to treat acute symptoms of asthma. solution for COPD patients is 15 mcg administered
twice a day (morning and evening) by nebulization.
The recommended initial dose is fluticasone/ A total daily dose greater than 30 mcg (15 mcg
salmeterol 100mcg/50mcg twice daily. Patients twice daily) is not recommended.
should completely rinse the mouth after each dose.
Brovana should be stored refrigerated in foil
74. (e) Tardive dyskinesia, dystonic reactions, pouches. Asthenia, fever, headache, vomiting,
akathisia, NMS (neuroleptic malignant syndrome) hyperkalemia, leukocytosis, nervousness, and
and drug-induced Parkinsonism are frequently tremor are reported side effects of Brovana.
reported side effects of antipsychotic drugs.
Priapism, a persistent, usually painful, erection that 77. (d) Aceon (Perindopril) is classified as an ACE
lasts for more than four hours and occurs without inhibitor. It is indicated for the treatment of
sexual stimulation, is not a frequently reported side essential hypertension.
effect of antipsychotics. It is usually reported with
Desyrel (Trazodone). In patients with essential hypertension, the
recommended initial dose is 4 mg once a day. The
dose may be titrated, as needed to a maximum of

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