Page 32 - FPGEE Management Q&A Book
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            particularly psychology, common examples are the      standardized methods to calculate utility values for
            Likert response scale and 1-10 rating scales in which   diseases.
            a person selects the number which is considered to
            reflect the perceived quality of a product.           36.(b) Cost Minimization Analysis (CMA):

            Standard gamble: The standard gamble is a method      This  type  of  analysis  is  used  to  examine  the  cost
            used  to  measure  health  utilities  of  varying  health   associated  with  two  or  more  alternatives  that  are
            states and allow for comparisons across populations   clinically  equivalent  in  terms  of  outcomes.
            and  different  clinical  settings.  These  health  utility   Equivalency must be established before conducting
            scores  are  useful  as  measures  of  outcome  for   an analysis. Furthermore, equivalency studies must
            quality of life and applicable to economic evaluation   include not only therapeutic outcomes but also the
            studies. Nonetheless, the measurement process can     type of adverse effects associated with therapies.
            be  cognitively  challenging,  and  controversies
            remain regarding raters and rating methods.           Cost  minimization  can  be  calculated  by  using  the
                                                                  following formula:
            Time-trade off: Time-Trade-Off (TTO) is a tool used
            in health economics to help determine the quality     Cost  (dollars)  of  intervention  A  <,  =,  or  >  Cost
            of life of a patient or group. The individual will be   (dollars) of intervention B
            presented with a set of directions such as:
                                                                  An  example  of  a  cost  minimization  analysis  would
            Imagine  that  you  are  told  that  you  have  10  years   be a comparison of two treatments with the same
            left to live. In connection with this you are also told   drug but different routes of administration.
            that you can choose to live these 10 years in your
            current health state or that you can choose to give   In both cases, if the therapeutic outcomes as well as
            up some life years to live for a shorter period in full   the incidence and type of adverse reactions remain
            health. Indicate with a cross on the line the number   the same, then one should chose the less expensive
            of years in full health that you think is of equal value   and laborious route of administration of the drug.
            to 10 years in your current health state.
                                                                  37.(d) All. Cost of Illness Analysis:
            The  line  usually  ranges  from  1  to  10  and  the
            person's score is calculated by dividing the number   This  type  of  evaluation  method  includes  all  costs
            corresponding to their cross by 10.                   and  consequences  related  to  treating  a  particular
                                                                  disease. It is really important to conduct a Cost of
            For example, if someone marks a cross at 4 on the     Illness  Analysis  before  initiating  further  economic
            TTO line, they would be given a TTO score of 0.4.     evaluation.  Advantages  of  using  Cost  of  Illness
            This  number  is  often  used  in  turn  to  calculate   Analysis:
            quality-adjusted life years or QALYs. In our example
            if this person were to live for 4 years at their current   1.  This  method  allows  researchers  to  collect  and
            health state this would be equal to 1.6 QALYs (4 x    assess disease specific data.
            .4).  QALYs  enable  health  care  decision  makers  to
            combine  mortality  and  morbidity  into  a  single   2.  It  provides  a  true  definition  of  the  particular
            interval scale.                                       illness.

            The major advantage of a cost-utility analysis is that   3.  It  provides  researchers  information  about
            it  is  the  only  analysis  method  that  calculates   epidermology and potential outcome of illness, and
            consequences or outcomes in terms of the quality      the consequences associated with the illness.
            of a patient’s life. The only disadvantage associated
            with  this  method  is  a  lack  of  uniform  or


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