Page 19 - Referance Guide For Pharmaceutical Calculations (Naplex, Fpgee and Ptce)

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The amount of KCl: Patient weight in kg = 120/2.2 = 54.54 kg

= 400 x 0.2 The dose of theophylline:
= 80 gm KCl = 80,000 mg KCl
= 0.2 x 54.54
Milliequivalents of KCl: = 10.90 mg per day

= 80,000 = 1073.82 mEqs of KCl 213.(d) 24 capsules.
74.5
The amount of KCl required:
208.(c) Ionized/Unionized = 100:1
= 180 x 0.1
= 18 gm
= + log
= 18000 mg

6 = 4 + log
The number of capsules required:

log = 2 = 18000 = 24 capsules

750
Salt (Ionized)/Acid (Unionized) = 100:1
214.(c) 0.329 minutes.
209.(c) 10:1
t 1/2 = 0.693
k
= − +

k = 0.693
t 1/2
6.5 = 14 − 8.5 +

k = 0.693
9.9 x 10 −2
= 6.5 − 5.5 = 1

k = 7 minutes.
Base (Unionized)/Salt (Ionized) = 10:1
k = 2.303 log Co
210.(c) 50 scoops. Patient is taking 1250 mg twice a t C
day (2500 mg/day).
t = 2.303 log 500
7 50
The number of scoops of Viracept required:
t = 2.303 log10
= 2500 = 50 scoops 7
50
t = 0.329 minutes.
211.(d) 57.6 days.
215.(c) 22.5 mg/5cc
The number of days required to finish a bottle:
The amount of drug in 10cc of 10% solution:
= 144000 mg = 57.6 days
2500 mg = 10 x 0.1
= 1 gm
212.(d) 10.9 mg. = 1000 mg

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