How much Lidocaine is required to prepare 1 : 1000, 30 cc of solution of Lidocaine?
1. (c) 1: 1000 generally interprets as 1 gm in 1000cc solution. The amount of lidocaine in 30cc of 1:1000 solution can be calculated as follows:
2.
How many cc of 75 % alcohol should mix with 10 %
of 1000cc alcohol to prepare 30% of 500cc alcohol
solution?
2. (c) To solve this type of problem, we need to use alligation method.
3.
If 60 gm of 1% hydrocortisone is mixed with 80 gm
of 2.5% of hydrocortisone, what is the % of hydrocortisone
in final mixture?
3.(b) Amount of Hydrocortisone in 60 gm, 1%
4.
If 1000 tablets of Risperdal 1 mg cost $ 2250 and
% mark up on prescription is 20, what would be the
retail price of 30 tablets?
4. (d) 1000 tablets of Risperdal 1mg cost $ 2250. The % mark up on prescription is 20%.
5.
If the ratio of ionized to unionized species of
drug is 103 and PKa = 2.2, what is the PH of the
solution?
5. (c) A pH of the solution can be found by the following formula:
6.
If dropper is calibrated to deliver 325 mg of iron
sulfate in 0.6 cc and adult dose of drug is 325
mg , what is the dose of a drug in cc for a 15 months-old
infant?
6. (c) 0.06cc. According to Fried’s rule:
7.
If the dose of a drug is 10 mg/kg/day, how many
250 mg/100cc ready infusion-bags require to fill
above order? Patient's weight is 156 lbs.
7. (c) Patient weight is 156 lbs, therefore weight in Kg would be 156/2.2 = 70.9 kg
8.How much of atropine is required to prepare 240cc
in such way that when 1 teaspoonful of the solution
is diluted to 1 pint gives 1 in 500 solution?
8. (b) To solve this kind of problem, we must first find out the amount of drug present in final solution.
9.
How much sodium bicarbonate powder is required to
prepare 240cc of 0.10 N solution of sodium bicarbonate?
a.
1.35 gm
9. (d) Gram equivalent weights of solute in 1 liter of solution is defined as normality, therefore 1N solution of sodium bicarbonate will contain 84 gms in 1000 cc. We want to find quantity of sodium bicarbonate in 240cc, 0.1 N solution:
10.
How many meq of Na+ are present in 0.9% 250cc normal
saline solution? [Na+ = 23, Cl- = 35.5]
10. (d) An amount of sodium chloride presents in 250 cc of 0.9% NaCl,
11.
If the probability of success in Null hypothesis
is 0.6, what is the probability of failure?
11. (d) The sum of probability of success and failure would be equal to 1 in Null hypothesis and can be expressed by following formula:
12.
How many grams of cocabutter are required to dispense
12 suppositories of tannic acid each weighing 2
gm and contain 400 mg of tannic acid?
12. (b) We want to dispense 12 suppositories each weighing 2gm and containing 400mg of tannic acic:
13.
What is the "mode" or "median" of the following
values?
13. (c) Median or Mode is generally expressed as a middle value of experiment, if number of values are even, then average of middle values should be considered. To find median or mode of experiment data, one should first arrange the data in ascending or descending order.
14.
If the concentration of reactant M is half in a
reaction that is third order in M, by what factor
will rate of reaction change?
14. (a) The concentration of reactant M is half in a reaction that is third order in kinetic:
15.
What is the rate of constant after 90 minutes if
the initial concentration of drug is 500mg/cc and
50mg/cc after 90 minutes? (First Order Kinetic)
15. (b) 0.025 min-1
16.
If the total body clearance of the patient is 2100cc/hr
and hepatic clearance is 300cc /hr, what is the
status of renal function in a patient?
16. (d) The status of renal function impairment can be expressed by creatinine clearance.
17.
How many grams of sodium chloride are required to
prepare 250cc of 1% boric acid solution to isotonic
with eye tears?
17. (c) Blood serum freezes at 0.520 C, and all solutions having this freezing point are isotonic with blood serum. 0.9% sodium chloride have the same freezing point that of blood serum.
