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Which of the following information about Folic acid is NOT TRUE?
 
a. It is indicated for prevention of neural tube defects in pregnancy.
 
b. It is indicated for the treatment of megaloblastic anemia.
 
c. The recommended daily allowance is 400 mg per day.
 
d. It is a water-soluble vitamin that has antidepressant, antiproliferative, anti-teratogenic, gingival and anti-inflammatory effects.
 
e. Erythema, pruritus, urticaria, irritability, nausea, bloating and flatulence are reported side effects of the vitamin.
 
Answer: (c) is NOT TRUE. Folic acid is a water-soluble vitamin that has antidepressant, antiproliferative, anti-teratogenic, gingival and anti-inflammatory effects.  It is indicated for prevention of neural tube defects in pregnancy. It is also indicated for the treatment of megaloblastic anemia. It shall not be used in presence of pernicious and megaloblastic anemia due to Vit B12 deficiency.
 
The recommended daily allowance is 400 mcg (NOT mg) per day. Erythema, pruritus, urticaria, irritability, nausea, bloating and flatulence are reported side effects of the drug.
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