Page 37 - Reference Guide For Foreign Pharmacy Licensing Exam Theory

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Steven Johnson Syndrome, nausea, vomiting, 24. (b) Argatroban (Acova) is a synthetic thrombin
diarrhea and abdominal pain are reported side inhibitor derived from L-arginine. It is indicated for
effects of drug. the treatment of heparin induced
thrombocytopenia. Bleeding is the major side effect
20. (b) Anagrelide (Agrylin) is classified as a platelets of the drug. Hypotension, cardiac arrest, rash and
aggregation inhibitor. It is indicated for the vasodilation are also reported with the therapy. The
treatment of polycythemia vera and chronic recommended dose is 2mcg/kg/min via continuous
myelogenous leukemia. It also reduces the platelets IV infusion.
count in essential thrombocythemia.
25. (c) Atropine is classified as an anti-cholinergic
Hemorrhage, heart failure, pulmonary fibrosis, CHF, agent. It blocks the acetylcholine effect on
cardiomyopathy, fibrillation and pericarditis are cholinergic receptors. It is indicated for the
reported side effects of drug. The recommended treatment of organophosphorus poisoning. Blurred
dose is 0.5 mg q.i.d. or 1 mg bid. vision, contact dermatitis, and increased intraocular
pressure of the eyes are reported side effects of
21. (c) Anastrozole (Arimidex) is classified as an drug.
antineoplastic agent. The growth of many breast
cancers is due to the stimulation of estrogen 26. (c) Azithromycin (Zithromax) is classified in the
receptors by estrogen. macrolide group of antibiotics. It is indicated for the
treatment of acute upper respiratory tract
The principal source of estrogen in postmenopausal infections. Ventricular arrhythmia and torsades de
women is conversion of androstenedione to estrone points in patients with prolonged QT intervals,
by aromatase in peripheral tissues, with further nausea, vomiting and anorexia are reported side
conversion to estradiol. Anastrozole is a effects of drug. The recommended dose is 500 mg
nonsteroidal aromatase inhibitor. for day 1, followed by 250 mg every day for 4 days.

Nausea, vomiting, diarrhea, abdominal pain and dry 27. (b) Baclofen (Lioresal) is classified as a centrally
mouth are reported side effects of drug. The acting muscle relaxant agent. It is indicated for the
recommended dose is 1 mg per day. treatment of multiple sclerosis and spasm
associated with the spinal cord of cerebral origin.
22. (c) Bleeding is the principal side effect of The recommended dose is 5-15 mg three times
Anistreplase. It is classified as a thrombolytic daily. Drowsiness, dizziness, lethargy, hypotension
enzyme. It is indicated for the treatment of acute and hallucination are reported side effects of drug.
myocardial infarction in adults and lysis of thrombi
obstructing coronary arteries. G.I. hemorrhage, 28. (b) Balsalazide (Colazal) is indicated for the
bleeding, arrhythmia and cardiac rupture are treatment of ulcerative colitis. It is a prodrug that is
reported side effects of the drug. The cleaved by colon-bacteria to release Mesalamine.
recommended dose is 30 units over 2-5 minutes Nausea, vomiting, diarrhea, hemorrhage and G.I.
through an IV line immediately after myocardial bleeding are reported side effects of drug. The
infarction occur. recommended dose is three (750 mg) capsules
three times a day for 8 weeks.
23. (b) Enoxaparin and Ardeparin are classified as
anticoagulants. They are low molecular weight 29. (c) Basiliximab (Simulect) is classified as an
heparins. They are indicated as prophylactic agents interleukin-2 receptor antagonist. It is indicated as a
for the treatment of deep vein thrombosis following prophylactic agent for renal transplantation. The
the knee replacement surgery. Nausea, vomiting, prolonged use of the drug may increase the risk of
allergic reaction, and bleeding are reported side opportunistic infection. The recommended dose is
effects of drugs. 20 mg within 2 hours prior to transplant surgery

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