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www.pharmacyexam.com                                                                  Krisman

            The recommended dose is 0.25 mg to 0.5 mg, three      13. (b) Amiodarone is classified as an antiarrhythmic
            times day.                                            agent.  It  is  indicated  for  the  treatment  of  life-
                                                                  threatening  ventricular  arrhythmia,  ventricular
            9. (b) Amantadine is classified as an antiviral agent.   fibrillation  and  ventricular  tachycardia.  The
            It  is  indicated  for  the  treatment  of  Parkinson’s   recommended dose is 200 mg to 400 mg per day.
            disease  and  influenza  A  viral  infections.  The   Pulmonary infiltrate and fibrosis, lung edema, cough
            recommended dose for treating Parkinson’s is 100      and bradycardia are reported side effects of drug.
            mg  bid;  up  to  400  mg/day.  Nausea,  vomiting,
            convulsion,  anorexia,  hypotension  and  xerostomia   14.  (b)   Amitriptyline   is   classified   as   an
            are reported side effects of the drug.                antidepressant. It is indicated for the treatment of
                                                                  depression. The recommended dose is 75 mg to 150
            10.  (b)  Amifostine  is  classified  as  an  organic   mg per day. Sedation, dizziness and anticholinergic
            thiophosphate  prodrug.  It  is  dephosphorylated  by   side effects have been reported with the drug.
            alkaline  phosphatase  in  tissues  to  the  active  free
            thiol  metabolite.  The  thiol  metabolite  reduces  the   15.  (b)  Amlodipine  (Norvasc)  is  classified  as  a
            toxic effects of Cisplatin.                           calcium  channel  blocker.  It  is  indicated  for  the
                                                                  treatment of hypertension. The recommended dose
                                                          2
            The recommended therapeutic dose is 910 mg/m          is  5  mg  to  10  mg  per  day.  Headache,  fatigue,
            given  once  daily  as  a  15-minute  I.V.  infusion;   lethargy,  hypotension  and  syncope  are  reported
            starting  within  30  minutes  prior  to  Cisplatin   side effects of drug.
            chemotherapy.
                                                                  16. (b) Amoxicillin is classified in the penicillin group
            The  principal  toxic  effect  of  Cisplatin  is  renal   of  antibiotic.  The  microorganism  induces  penicillin
            toxicity. Hypotension, severe nausea and vomiting,    resistance  by  producing  beta  lactamase  enzymes
            dizziness,  somnolence  and  toxic  epidermal         which inactivates the beta-lactam ring of penicillin.
            necrolysis are reported side effects of Amifostine.   Potassium  clavulanate  inactivates  beta  lactamase
                                                                  enzyme and increases the effect of Amoxicillin.
            11. (b) Amikacin is classified in the aminoglycoside
            group of antibiotics. It is indicated for treatment of   17. (c) Amphetamine is indicated for the treatment
            gram negative bacterial infections.                   of  ADHD  (Attention  Deficit  Hyperactivity  Disorder)
                                                                  and narcolepsy. The recommended dose is 5 to 20
            The  principal  side  effect  of  the  drug  is  renal  and   mg 1 to 3 times a day. Insomnia, CNS stimulation,
            ototoxicities.                                        tachycardia  and  restlessness  are  reported  side
                                                                  effects of drug.
            The recommended dose is 15 mg/kg/day in two to
            three divided doses, every 8 to 12 hours for 7 to 10   18. (b) Amphotericin B is classified as an antifungal
            days. The trough serum concentration of Amikacin      agent. It is indicated for the treatment of systematic
            must  be  maintained  below  10  mcg/ml  to  avoid    candidiasis,   cryptococcosis,   histoplasmosis,
            toxicity.                                             blastomycosis, and mucormycosis.

            12. (c) Amiloride is classified as a potassium sparing   Fever, shaking chills, hypokalemia, renal failure, and
                                  +
                                      +
            diuretic.  It  inhibits  Na ,  K   -ATP ase  pump.  It  is   respiratory failure are reported side effects of drug.
            indicated  for  the  treatment  of  hypertension  or   The recommended dose is 0.25-0.3 mg/kg over 2 to
            edema due to CHF. The recommended dose is 5 mg        6 hours.
            to  10  mg  per  day.  Hyperkalemia,  hyponatremia,
            hypochloremia,  dizziness,  nausea  and  diarrhea  are   19. (a) Amprenavir is classified as an antiviral agent.
            reported side effects of drug.                        It  is  indicated  for  the  treatment  of  HIV  infection.
                                                                  The recommended dose is 1200 mg by mouth bid.


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