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The recommended dose is 0.25 mg to 0.5 mg, three 13. (b) Amiodarone is classified as an antiarrhythmic
times day. agent. It is indicated for the treatment of life-
threatening ventricular arrhythmia, ventricular
9. (b) Amantadine is classified as an antiviral agent. fibrillation and ventricular tachycardia. The
It is indicated for the treatment of Parkinson’s recommended dose is 200 mg to 400 mg per day.
disease and influenza A viral infections. The Pulmonary infiltrate and fibrosis, lung edema, cough
recommended dose for treating Parkinson’s is 100 and bradycardia are reported side effects of drug.
mg bid; up to 400 mg/day. Nausea, vomiting,
convulsion, anorexia, hypotension and xerostomia 14. (b) Amitriptyline is classified as an
are reported side effects of the drug. antidepressant. It is indicated for the treatment of
depression. The recommended dose is 75 mg to 150
10. (b) Amifostine is classified as an organic mg per day. Sedation, dizziness and anticholinergic
thiophosphate prodrug. It is dephosphorylated by side effects have been reported with the drug.
alkaline phosphatase in tissues to the active free
thiol metabolite. The thiol metabolite reduces the 15. (b) Amlodipine (Norvasc) is classified as a
toxic effects of Cisplatin. calcium channel blocker. It is indicated for the
treatment of hypertension. The recommended dose
2
The recommended therapeutic dose is 910 mg/m is 5 mg to 10 mg per day. Headache, fatigue,
given once daily as a 15-minute I.V. infusion; lethargy, hypotension and syncope are reported
starting within 30 minutes prior to Cisplatin side effects of drug.
chemotherapy.
16. (b) Amoxicillin is classified in the penicillin group
The principal toxic effect of Cisplatin is renal of antibiotic. The microorganism induces penicillin
toxicity. Hypotension, severe nausea and vomiting, resistance by producing beta lactamase enzymes
dizziness, somnolence and toxic epidermal which inactivates the beta-lactam ring of penicillin.
necrolysis are reported side effects of Amifostine. Potassium clavulanate inactivates beta lactamase
enzyme and increases the effect of Amoxicillin.
11. (b) Amikacin is classified in the aminoglycoside
group of antibiotics. It is indicated for treatment of 17. (c) Amphetamine is indicated for the treatment
gram negative bacterial infections. of ADHD (Attention Deficit Hyperactivity Disorder)
and narcolepsy. The recommended dose is 5 to 20
The principal side effect of the drug is renal and mg 1 to 3 times a day. Insomnia, CNS stimulation,
ototoxicities. tachycardia and restlessness are reported side
effects of drug.
The recommended dose is 15 mg/kg/day in two to
three divided doses, every 8 to 12 hours for 7 to 10 18. (b) Amphotericin B is classified as an antifungal
days. The trough serum concentration of Amikacin agent. It is indicated for the treatment of systematic
must be maintained below 10 mcg/ml to avoid candidiasis, cryptococcosis, histoplasmosis,
toxicity. blastomycosis, and mucormycosis.
12. (c) Amiloride is classified as a potassium sparing Fever, shaking chills, hypokalemia, renal failure, and
+
+
diuretic. It inhibits Na , K -ATP ase pump. It is respiratory failure are reported side effects of drug.
indicated for the treatment of hypertension or The recommended dose is 0.25-0.3 mg/kg over 2 to
edema due to CHF. The recommended dose is 5 mg 6 hours.
to 10 mg per day. Hyperkalemia, hyponatremia,
hypochloremia, dizziness, nausea and diarrhea are 19. (a) Amprenavir is classified as an antiviral agent.
reported side effects of drug. It is indicated for the treatment of HIV infection.
The recommended dose is 1200 mg by mouth bid.
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