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1. (b) Abacavir (Ziagen) is classified as an antiviral The recommended dose for treating
agent. It is indicated for the treatment of AIDS. The acetaminophen overdosage is 10ml of 20% solution
recommended therapeutic dose of the drug is 300 or two 10 ml of 10% solution 3-to-4 times day via
mg bid. The principal side effect of the drug is nebulization.
hypersensitivity reaction. Liver failure, renal failure
and severe hypotension are also reported. Bronchial and tracheal irritation, tightness in chest,
fever, and drowsiness are reported side effects of
2. (b) Acarbose (Precose) inhibits pancreatic the drug.
amylase and alpha glucosidase hydrolase enzymes.
This causes delayed glucose absorption resulting in 6. (b) Alendronate Na is classified as a
a smaller increase in blood glucose following meals. bisphosphonate. It is indicated for the treatment of
osteoporosis and Paget’s disease of bone.
It is indicated for the treatment of type II diabetes
mellitus. The recommended therapeutic dose of the The recommended dose of the drug is 5 to 10 mg
drug is 25 mg to 100 mg, one to three times day once a day in the morning before the first food,
with the first bite of each main meal. beverage, or medication of the day, with 6 to 8 oz
of plain water.
Diarrhea, flatulence, and abdominal pain are
reported side effects of the drug. Esophageal ulcers, dysphagia, abdominal pain and
flatulence are reported side effects of the drug.
3. (b) Atenolol, Acebutolol, Metoprolol and
Betaxolol are classified as specific Beta antagonists. 1. Alendronate Na must be taken with plain water
They specifically block beta-1 receptors. only; orange juice, mineral water or other liquids
are not allowed since they may interfere with the
They can be safely used to treat hypertension in absorption of drug.
patients suffering from asthma. The recommended
therapeutic dose of Acebutolol is 400 mg per day. 2. The patient must not lie down for at least 30
minutes after taking the drug to facilitate drug
Severe persistent bradycardia is the principal side delivery to the stomach and to reduce esophageal
effect of Acebutolol. irritation.
4. (b) Acetazolamide (Diamox) is classified as a 3. Alendronate Na must not be taken with antacids
carbonic anhydrase inhibitor. It is indicated for or calcium supplements since they may interfere
treatments of glaucoma, acute motion sickness, with the absorption of the Alendronate.
edema and heart failure.
7. (a) The principal metabolite of Allopurinol is
Bone marrow suppression, hemolytic anemia, Oxipurinol. It is indicated for the treatment of gout.
Steven Johnson Syndrome, anorexia, and It is a potent inhibitor of xanthine oxidase enzyme.
constipation are reported side effects of the drug.
This enzyme is involved in the synthesis of uric acid.
5. (a) Acetylcysteine (Mucomyst) is indicated for the The recommended dose of drug is 200 mg to 600
treatment of acetaminophen poisoning. It reduces mg per day. Skin rash, nausea, vomiting, and
liver injury due to acetaminophen overdosage by diarrhea are reported side effects of the drug.
maintaining adequate glutathione levels.
8. (b) Alprazolam is classified as an antianxiety
It is also indicated for the treatment of chronic agent. It is indicated for the treatment of anxiety,
emphysema with bronchitis and chronic asthmatic panic disorder and agoraphobia with social phobia.
bronchitis.
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