9
(b) 33 grams. For calculations of this
type the allegation method is very useful.
We want to prepare 500 gm of 0.2 % salicylic
acid by mixing talc (0 %) powder with 3 %
of Salicylic acid powder.
3 % salicy 0.2 (3 % sali)
0.2 %
0
% talc (no salicy) 2.8 (0% sali)
Total 3.0 (0.2 % sali)
We
want to find out how many grams of 3 % salicylic
acid required
Total
parts of 0.2% sali Parts of 3 % sali
3 parts 0.2 parts 500 ?
500
x 0.2 / 3 = 33 grams of 3% salicylic acid
required.
10
(b) Plavix (Clopidrogel) is a blood
thinning agent. Agents of this class generally
act by inhibiting aggregation of platelets
which is thought to be the primary mechanism
of blood clotting. It is indicated for prevention
of heart stroke in patients with CHF.
11
(b) Asthma is characterized by increased
responsiveness of trachea and bronchi to various
stimuli and narrowing of airways. It is associated
with shortness of breath, chest tightness,
wheezing and coughing. The Beta-2 receptors
stimulation generally dilates the bronchial
smooth muscles and helps in controlling asthma.
Beta-2
receptors blockers generally constrict the
smooth muscles of bronchi and may even aggregate
asthma.
Metoprolol
is a Beta-1 and Beta-2 receptor blockers indicated
for treatment of hypertension and should be
carefully prescribed in patient with asthma.
Other choices such as Accolate and Atrovent
are indicated for treatment of asthma.
12
(b) The prescription of CII controlled
drugs should be dispensed with specific quantity
mentioned on prescription by physician. MS-contin
is a controlled II drug and therefore correct
dispensing quantity would be 60.
13
(b) Prescription of controlled drugs
III, IV and V cannot be refilled more than
5 times. A patient must bring a new prescription
after this allowable refill is executed. Prescriptions
older than 6 months require a new prescription
to fill.
14
(c) Otocort otic solution is intended
for ear use only. It should not be applied
to eyes and therefore the auxiliary label
For ear use only is required.
15
(c) Tamsulosin is the generic name
of Flomax. It is indicated for treatment of
B.P.H. All of the rest of the choices are
colony stimulator agents. They generally help
in stimulation of erythrocyte and granulocytes.
16
(d) 150 cc. Lanoxin is available in
0.05 mg/ml. Patient is taking 0.25 mg per
day.
Drug
ml of solution
0.05 mg 1 ml
0.25 mg ?
0.25
x 1 / 0.05 = 5ml
for
30 days supply = 30 x 5cc = 150cc
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